Djeukeu Kemmoe Charlie, H. L. Maza, Kenmogne Kouam Ariane, Sewald Norbert, W. J. Duplex, Vardamides Juliette Catherine
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引用次数: 1
Abstract
One new coumarinolignan, cleomiscosin F (1) along with ten known compounds namely 3,4-secotirucalla-4(28),7,24-trien-21-hydroxy-21,23-epoxy-3-oic acid (2), 3,4-secotirucalla-4(28),7,24-trien-3,21-dioic acid (3),ceramid A (4),ceramid B (5), mayombensin (6),aridanin (7), stigmasterol and β-sitosterol and their glucosides were isolated from the seeds and roots of Leplaea mayombensis (Meliaceae).Thestructures of the compounds were elucidated based on the interpretation of their spectroscopic data. Some of the isolated compounds (3, 4 and 5) were tested in vitro against bacteria strains Escherichia coli, Bacillus subtilis, Pseudomonas agarici, and Micrococcus luteus. Compound 3 displayed good activity against Bacillus subtilis, Micrococcus luteus, and Pseudomonas agarici with MIC values of 1.7, 2.3 and 9.8µM, respectively; while compound 4 showed significant activity against Micrococcus luteus with MIC value of 11.9µM.
期刊介绍：
Town Planning Review has been one of the world"s leading journals of urban and regional planning since its foundation in 1910. With an extensive international readership, TPR is a well established urban and regional planning journal, providing a principal forum for communication between researchers and students, policy analysts and practitioners. To mark TPR’s centenary in 2010, it is proposed to publish a series of ‘Centenary Papers’ -- review papers that record and reflect on the state of the art in a range of topics in the general field of town and regional planning.
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