MOLECULAR BASIS OF OUR ORGANISM’S INTOLERANCE TO LACK OF GENETIC MATERIAL

S. Boumendjel
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引用次数: 0

Abstract

Chromosomal fragments deletions are very harmful. They are almost lethal even in the presence of a normal homologue. Autosomal monosomies are incompatible with survival. However, micro-deletions are less fatal but they often produce clinical syndromes With characteristic phenotypes. Thus, a question rises: why does our organism not tolerate the lack of genetic material ? The present work, is a profound investigation on the molecular basis of the intolerance of our organism to the lack of genetic material. The subject under discussion has never been dealt with before. Up to now, no article had been published on this matter.
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我们的生物体不耐受缺乏遗传物质的分子基础
染色体片段缺失是非常有害的。即使存在正常同源物,它们也几乎是致命的。常染色体单体切除与存活率不相容。然而,微小缺失的致命性较低,但它们通常会产生具有特征表型的临床综合征。因此,一个问题出现了:为什么我们的生物体不能容忍遗传物质的缺乏?目前的工作,是对我们的生物体对缺乏遗传物质的不容忍的分子基础的深入调查。讨论中的这个问题以前从未涉及过。到目前为止,还没有关于此事的文章发表。
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