Chemical composition and biologic activities of different preparations of Japanese quince (Chaenomeles japonica)

K. Moneva, S. Gancheva, S. Valcheva-Kuzmanova
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Abstract

Abstract The hectic pace of life and growing threat of cardiovascular, metabolic and neoplastic diseases highlight the demand for products with natural origin that could simultaneously be part of the balanced diet and improve human’s health. A promising finding in this respect is the Japanese quince – Chaenomeles japonica. It is an ancient plant with eastern origin, but the scientific knowledge about it has only recently started to build up. The aim of this review is to gather scientific data about chemical composition and biologic activities of Chaenomeles japonica and to provide an insight into the possible prophylactic and therapeutic applications of the plant. The gathered and summarized information concerning Japanese quince shows that preparations of different parts of the plant, especially fruits and leaves, possess biologic properties that could be of exceptional nutritional and medicinal value. Antiinflammatory, antiproliferative, antimicrobial, carbohydrate metabolism-modulating activities in in vitro studies as well as safety profile, influence on neuropsychology and behavior in animal models are discussed. This review outlines the prophylactic and therapeutic effects of Chaenomeles japonica, as well as the chemical composition that stands behind them, and aims to serve as a basis for further investigations of the medicinal plant’s potential.
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木瓜(Chaenomeles japonica)不同制剂的化学成分及生物活性
随着生活节奏的加快,心血管、代谢和肿瘤疾病的威胁日益增加,人们对天然产品的需求越来越大,这些产品既可以成为均衡饮食的一部分,又可以改善人类的健康。在这方面一个有希望的发现是日本的木瓜——Chaenomeles japonica。它是一种古老的植物,起源于东方,但关于它的科学知识直到最近才开始建立起来。本文旨在收集有关木瓜的化学成分和生物活性的科学资料,为该植物的预防和治疗应用提供参考。收集和总结的资料表明,该植物的不同部分,特别是果实和叶子的制剂,具有特殊的营养和药用价值的生物学特性。本文讨论了抗炎、抗增殖、抗菌、体外碳水化合物代谢调节活性以及动物模型的安全性、对神经心理学和行为的影响。本文综述了木瓜的预防和治疗作用及其背后的化学成分,旨在为进一步研究该药用植物的潜力奠定基础。
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15
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4 weeks
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