Medication errors with influencing factors of polypharmacy among elderly patients using Calcium Chanel Blockers.

Shagufta Nesar, M. Shoaib, Kiran Rafiq, M. Mughal, Tayyaba Mumtaz, Ishrat Younus, Arfa Akram
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Abstract

Background: Geriatrics refers to age-related health changes and consequently causes complications in polypharmacy, generalizing prescribing patterns. The study aimed to investigate the pervasiveness of medication inaccuracies along with drug interactions. Methodology: Out of 450 prescriptions only 210 were selected that contained Calcium Channel Blocker (CCB) and other drugs. Drug-drug interactions were articulated by Micromedex 2.0, and the harm score was determined by National Coordinating Council for Medication Error Reporting and Prevention. Results: The outcomes revealed that 645 medication errors were identified and multiple errors were present in a single prescription. The most frequent error was unstated patient's weight (98.6%) proceeds from drug-drug interactions (66.7%). According to the harm score, 36.66% of prescriptions were placed in category D, there was a statistically significant association between the drug-drug interaction and the number of prescribed drugs (p<0.0001). Conclusion: The prime solution is that the physicians should be facilitated withal trainings about drug interactions and prescription writing skills according to WHO guidelines or other recognized standards.
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老年钙受体阻滞剂用药错误及影响因素分析。
背景:老年医学是指与年龄相关的健康变化,从而导致多药治疗的并发症,推广了处方模式。这项研究旨在调查药物不准确以及药物相互作用的普遍性。方法:在450个处方中,只有210个处方含有钙通道阻滞剂(CCB)和其他药物。药物相互作用由Micromedex 2.0阐明,危害评分由国家药物错误报告和预防协调委员会确定。结果:结果显示,645个药物错误被发现,单个处方中存在多个错误。最常见的错误是未说明的患者体重(98.6%)来自药物相互作用(66.7%)。根据危害评分,36.66%的处方属于D类,药物-药物相互作用与处方药数量之间存在统计学显著相关性(p<0.0001)。结论:主要解决方案是,应根据世界卫生组织指南或其他公认标准,为医生提供药物相互作用和处方书写技能方面的培训。
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审稿时长
12 weeks
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