Complex techniques of eyelid reconstruction following extensive basal cell carcinoma resection

A. Rokohl, A. Kopecký, P. A. W. Matos, Yongwei Guo, V. Kakkassery, L. Heindl
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Abstract

Basal cell carcinoma (BCC) is one of the most common malignant tumors overall and even the most common malignant tumors in ophthalmology. In most cases, surgical resection followed by an ophthalmoplastic reconstruction is the current gold standard for the treatment of periocular BCC. Histopathologic analysis can be performed both as a frozen section examination, Mohs micrographic surgery, or as a rapid embedding analysis, depending on the surgeon’s preference or the in-house standard. A histopathologic workup is essential not only for confirming the diagnosis and determining resection status but especially for identifying infiltrating growing subtypes, as this also influences postoperative follow-up and prognosis. A wide range of various reconstruction methods allow individualized defect coverage with mostly good cosmetically and functionally results. The basic principle is to restore the anatomy with an anterior and posterior eyelid lamella. The selection of the appropriate technique depends not only on the vertical and horizontal defect size, defect localization, or potential eyelid edge involvement but also significantly on the patient’s age, available tissue (e.g., skin), the patient’s preference, and especially the surgeon’s experience. For smaller, partial, or penetrating defects, direct wound closure can be performed. However, for greater defects more complex reconstruction techniques including Tenzel’s rotational plasty, Hughes flap, CutlerBeard plastic, Mustardé lid Switch flap, tarsomarginal grafts according to Huebner, or V-Y glabella flap are necessary, dependently on the size and the location of the defect. However, in advanced findings with infiltration of the orbit, orbital exenteration is unavoidable in some cases. Postoperative regular follow-up is essential to identify potential complications in an early stage.
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基底细胞癌大面积切除后眼睑重建的复杂技术
基底细胞癌(Basal cell carcinoma, BCC)是最常见的恶性肿瘤之一,也是眼科最常见的恶性肿瘤。在大多数情况下,手术切除后眼球成形术重建是目前治疗眼周基底细胞癌的金标准。组织病理学分析既可以作为冷冻切片检查,莫氏显微摄影手术,也可以作为快速包埋分析,这取决于外科医生的偏好或内部标准。组织病理学检查不仅对于确认诊断和确定切除状态至关重要,而且对于确定浸润性生长亚型尤为重要,因为这也影响术后随访和预后。广泛的各种重建方法允许个性化的缺陷覆盖,大多数是良好的美容和功能的结果。基本原理是用前、后睑板恢复解剖结构。选择合适的技术不仅取决于垂直和水平缺损的大小、缺损的位置或潜在的眼睑边缘受损伤,而且还取决于患者的年龄、可用的组织(如皮肤)、患者的偏好,尤其是外科医生的经验。对于较小的、局部的或穿透性的缺陷,可以直接缝合伤口。然而,对于更大的缺陷,根据缺陷的大小和位置,需要更复杂的重建技术,包括Tenzel旋转成形术、Hughes皮瓣、cultlerbeard塑料、mustardshall lid Switch皮瓣、Huebner的睑缘移植物或V-Y眉骨瓣。然而,在眼眶浸润的晚期发现,在某些情况下,眼眶摘除是不可避免的。术后定期随访对于早期发现潜在并发症至关重要。
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