Comment on the Importance of Documenting Drug Solubility Measurement Methodology, Including Characterizing the Physical Form of the Solute, for Meaningful Understanding, Interpretation, and Reporting of Solubility Data

Abstract

T his commentary continues the discussion initiated in a previous article entitled “Comment on the Importance of Data Transparency, Openness, and Reproducibility in Dissolution Science and Technology” (1). As a follow-up, this commentary more specifically provides a scan of current practices in the literature that are applicable to solubility data reported in Dissolution Technologies, with the goal of enhancing reproducibility and meaningful interpretations of these data.