Fontan-related morbidity and paced QRS duration: A case series

IF 0.6 Q4 PEDIATRICS PROGRESS IN PEDIATRIC CARDIOLOGY Pub Date : 2023-06-01 DOI:10.1016/j.ppedcard.2023.101641
John F. Keaney III , M. Abigail Simmons , Robert W. Elder , Cheyenne M. Beach
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Abstract

Permanent pacemakers have been associated with Fontan-related morbidity and mortality. Longer QRS duration and QRS prolongation over time may be associated with poorer outcomes in Fontans patients. We present a series of eleven Fontan patients with ventricular pacing on serial electrocardiograms (ECGs), including seven with Fontan-related morbidity. Paced QRS duration increased over time in nearly all patients, with several having extremely long QRS durations at the end of the follow-up period. We explore the role that paced QRS duration may play in Fontan-related morbidity and mortality and its potential as a therapeutic target for patient management.

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Fontan相关发病率和起搏QRS持续时间:一个病例系列
永久性起搏器与fontan相关的发病率和死亡率有关。较长的QRS持续时间和QRS随时间的延长可能与Fontans患者较差的预后相关。我们在一系列心电图(ECGs)上报道了11例Fontan患者的心室起搏,其中包括7例Fontan相关疾病。在几乎所有患者中,有节奏的QRS持续时间随着时间的推移而增加,有几个患者在随访期结束时QRS持续时间非常长。我们探讨有节奏的QRS持续时间在fontan相关发病率和死亡率中可能发挥的作用,以及它作为患者管理治疗靶点的潜力。
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来源期刊
CiteScore
0.90
自引率
11.10%
发文量
69
审稿时长
75 days
期刊介绍: Progress in Pediatric Cardiology is an international journal of review presenting information and experienced opinion of importance in the understanding and management of cardiovascular diseases in children. Each issue is prepared by one or more Guest Editors and reviews a single subject, allowing for comprehensive presentations of complex, multifaceted or rapidly changing topics of clinical and investigative interest.
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