Lenalidomide in cancer cachexia: a randomized trial of an anticancer drug applied for anti‐cachexia

D. Blum, C. Hertler, R. Oberholzer, S. Wolf-Linder, M. Joerger, C. Driessen, F. Strasser
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引用次数: 4

Abstract

Cancer cachexia (CC) impacts quality of life, physical function, anticancer treatment response, and survival. Inflammation is a prominent pathomechanism of CC. This small‐scale study sets out to investigate the immunomodulatory drug lenalidomide in inflammatory CC in a randomized, double‐blind, placebo‐controlled trial.
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来那度胺治疗癌症恶病质:一项抗恶病质抗癌药物的随机试验
癌症恶病质(CC)影响生活质量、身体功能、抗癌治疗反应和存活率。炎症是CC的一种重要病理机制。这项小规模研究旨在通过一项随机、双盲、安慰剂对照试验,研究免疫调节药物来那度胺在炎症性CC中的作用。
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Issue Information Altered skeletal muscle density: a matter of increased fat infiltration or reduced muscle mass? Uncorrected and subcutaneous fat-corrected echo intensities are similarly associated with magnetic resonance imaging per cent fat A genome wide association study to identify germline copy number variants associated with cancer cachexia: a preliminary analysis Combined orchiectomy and limb immobilization recapitulate early age-related changes to skeletal muscle in mice
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