Current immunotherapies for multiple sclerosis and neuromyelitis optica spectrum disorders: the similarities and differences

Lujun Zhang, Jingyuan Tian, Bin Li
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引用次数: 7

Abstract

Multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD) are autoimmune demyelinating diseases of the central nervous system. Neuromyelitis optica was considered a variant of MS until the discovery of NMO-IgG in 2004, which changed our understanding of the pathophysiology of NMOSD. This review focuses on the similarities and differences in the immune treatments of MS and NMOSD.
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目前多发性硬化症和视神经脊髓炎谱系障碍的免疫疗法的异同
多发性硬化症(MS)和视神经脊髓炎谱系障碍(NMOSD)是中枢神经系统自身免疫性脱髓鞘疾病。在2004年发现NMO-IgG之前,视神经脊髓炎一直被认为是多发性硬化症的一种变体,这改变了我们对NMOSD病理生理的认识。本文就MS与NMOSD免疫治疗的异同作一综述。
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