Cardiovascular Complications and Composition of the Intestinal Microbiome in Patients with Type 2 Diabetes

Abstract

Background: The composition of the gut microbiome appears to exert an influence on the development of cardiovascu lar complications (CVCs). We investigate here the relation ship between the composition of the gut microbiome and the prevalence of CVCs in patients with type 2 diabetes. Methods: Demographic characteristics, routine laboratory results, data on the prevalence of CVCs and the compo sition of the gut microbiome assessed by 16S rRNA se quencing logistic butyrate-producing bacteria. These findings may reflect an impaired intestinal barrier and should be investigated in future prospective studies. Glo merular Filtration Percutaneous Transluminal Angioplasty; Ischemic TMA: Trimethylamine