(2Z,5Z)-5-((3-(Benzofuran-2-yl)-1-phenyl-1H-pyrazol-4-yl)methylene)-2-((4-methoxyphenyl)imino)-3-phenylthiazolidin-4-one

IF 0.6 Q4 CHEMISTRY, ORGANIC Molbank Pub Date : 2023-06-09 DOI:10.3390/m1665
Bakr F. Abdel-Wahab, Hanan A. Mohamed, Benson M. Kariuki, Gamal A. El-Hiti
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引用次数: 0

Abstract

The reaction of a 1:1 mixture of 3-(benzofuran-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde (1) and 2-((4-methoxyphenyl)imino)-3-phenylthiazolidin-4-one (2) in anhydrous ethanol containing piperidine as a catalyst under reflux for 4 h gave (2Z,5Z)-5-((3-(benzofuran-2-yl)-1-phenyl-1H-pyrazol-4-yl)methylene)-2-((4-methoxyphenyl)imino)-3-phenylthiazolidin-4-one (3), C34H24N4O3F, in 82% yield. The structure of the newly synthesized heterocycle was confirmed via X-ray diffraction and spectral analyses.
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(2 z, 5 z) 5 - ((3 - (Benzofuran-2-yl) 1-phenyl-1h-pyrazol-4-yl)亚甲基)- 2 - ((4-methoxyphenyl)亚氨基的)3-phenylthiazolidin-4-one
3-(苯并呋喃-2-基)-1-苯基-1H-吡唑-4-甲醛(1)和2-((4-甲氧基苯基)亚氨基)-3-苯基噻唑烷-4-酮(2)在含有哌啶作为催化剂的无水乙醇中的1:1混合物在回流下反应4小时,得到(2Z,5Z)-5-(((3-(苯并呋喃-2-基]-1-苯基-1H吡唑-4-基)亚甲基)-2-((4-甲基苯基)亚氨基)-3-苯基吡唑-4-酮(3),C34H24N4O3F,产率82%。通过X射线衍射和光谱分析证实了新合成的杂环的结构。
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来源期刊
Molbank
Molbank Chemistry-Physical and Theoretical Chemistry
CiteScore
0.70
自引率
33.30%
发文量
174
审稿时长
11 weeks
期刊介绍: •organic synthesis •biosynthesis •extraction and purification •natural product derivatives •structural elucidation (X-ray crystallography, NMR, etc.)
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