Corticosteroid treatment versus surgical treatment of chronic rhinosinusitis with nasal polyposis

Amal A. El-Emam, Magda Mohamed, Doaa Saif Eldin, Soaad Mostafa
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Abstract

Background and Aim The definition of chronic rhinosinusitis is inflammation of the nose and paranasal sinuses characterized by two or more symptoms like nasal obstruction, congestion of nasal mucosa, reduction or loss of smell, facial pain, and either endoscopic signs of polyps edema or mucosal obstruction primarily in middle meatus, maybe computed tomography changes showing mucosal changes within the ostiomeatal complex and sinuses. The aim of this study was to assess the outcome of medical treatment in comparison with functional endoscopic sinus surgery as a treatment of allergic nasal polyposis. Patients and methods A prospective study was carried out at Al-Zahraa University Hospital, Faculty of Medicine for Girls, Al-Azhar University, which included 40 patients (30 males and10 females) divided into two groups, mean age of group A (36.9±10.2) and mean age of group B (39.8±9). Results There is no statistically significant difference between both groups as regards runny nose, nasal obstruction, postnasal drip, smell sensation, taste sensation, sneezing, fascial pain, or headache before intervention. There is a statistically significant difference between both groups after intervention (by medication or surgery) as regards runny nose (P=0.034), nasal obstruction was highly significant (P=0.001), and smell sensation was highly significant (P=0.005), while there was no significant difference between both groups as regards other symptoms like postnasal drip, fascial pain, headache, sneezing, and taste sensation (P>0.05). Conclusion We conclude from our data that medical treatment was cost-effective and time-saving. Many patients who received medical treatment responded well to the point of refusing any surgical procedure, functional endoscopic sinus surgery is essential when medical treatment was not sufficient in improving manifestations.
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皮质类固醇治疗与外科治疗慢性鼻窦炎合并鼻息肉病
背景和目的慢性鼻窦炎的定义是鼻和副鼻窦的炎症,其特征是两种或多种症状,如鼻阻塞、鼻粘膜充血、嗅觉减退或丧失、面部疼痛,以及息肉水肿或粘膜阻塞的内镜症状,主要发生在中道,计算机断层扫描可能显示窦口复合体和鼻窦内的粘膜变化。本研究的目的是评估药物治疗与功能性鼻内镜手术治疗过敏性鼻息肉的疗效。患者和方法在Al Zahraa大学医院,Al Azhar大学女子医学院进行了一项前瞻性研究,包括40名患者(30名男性和10名女性),分为两组,A组平均年龄(36.9±10.2)和B组的平均年龄(39.8±9),干预前的鼻塞、鼻后滴漏、嗅觉、味觉、打喷嚏、筋膜疼痛或头痛。干预(通过药物或手术)后,两组在流鼻涕(P=0.034)、鼻塞高度显著(P=0.001)和嗅觉高度显著(P=0.005)方面存在统计学显著差异,而在鼻后滴漏、筋膜疼痛、头痛、打喷嚏等其他症状方面无显著差异,结论从我们的数据中我们得出结论,药物治疗是划算和省时的。许多接受药物治疗的患者反应良好,拒绝任何外科手术,当药物治疗不足以改善表现时,功能性鼻内镜鼻窦手术至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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审稿时长
34 weeks
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