Nem kódoló RNS-ek mint hormonok? A hormonfogalom lehetséges bővülése • Non-Coding RNAs as Hormones? The Potential Expansion of the Hormone Concept

Abstract

Coding RNAs play an important role in gene expression which is the translation of information coded in DNA to proteins. Non-coding RNAs, on the other hand, function as important regulatory molecules. MicroRNAs (miRNAs) are the most known members of this family, taking part in the silencing of genes (translational repression). Hormones classically regulate cells and tissues in the body far from the hormone-producing cells. Until recently, we had no information on the potential hormone-like activity of miRNAs, however, miRNAs released into the circulation might *