{"title":"Extranodal nasal-type NK/T cell lymphoma with lipoid pneumonia: report of one case and review of literature","authors":"Jiali Zhu, Yan Zhang","doi":"10.3760/CMA.J.CN115356-20190725-00142","DOIUrl":null,"url":null,"abstract":"目的 \n提高对结外鼻型NK/T细胞淋巴瘤合并类脂性肺炎的认识，防止误诊、漏诊。 \n \n \n方法 \n回顾性分析江苏省肿瘤医院收治的1例结外鼻型NK/T细胞淋巴瘤合并类脂性肺炎患者的诊疗经过，并复习相关文献。 \n \n \n结果 \n该患者抗肿瘤过程中出现新的肺部病灶，考虑炎症，不排除肿瘤浸润的可能，但抗感染治疗无效，病灶逐渐进展，疑诊为肿瘤浸润。后经反复询问病史并行肺活组织检查，确诊为类脂性肺炎，经激素等治疗后逐渐好转。 \n \n \n结论 \n结外鼻型NK/T细胞淋巴瘤合并类脂性肺炎临床上较为罕见，临床表现无特异性，肺活组织检查有助于诊断。","PeriodicalId":59994,"journal":{"name":"","volume":"29 1","pages":"183-185"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.CN115356-20190725-00142","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Objective: To improve the understanding of extranodal nasal type NK/T cell lymphoma with lipoid pneumonia and prevent misdiagnosis and missed diagnosis. Method: A retrospective analysis was conducted on the diagnosis and treatment of a patient with extranodal nasal type NK/T cell lymphoma complicated with lipoid pneumonia admitted to Jiangsu Cancer Hospital, and relevant literature was reviewed. As a result, the patient developed new lung lesions during the anti-tumor process, and considering inflammation, the possibility of tumor infiltration was not ruled out. However, the anti infection treatment was ineffective, and the lesion gradually progressed, suspected to be tumor infiltration. After repeatedly inquiring about the medical history and conducting lung biopsy, the diagnosis was confirmed as lipoid pneumonia. After treatment with hormones, it gradually improved. Conclusion: Extranodal nasal type NK/T cell lymphoma combined with lipoid pneumonia is relatively rare in clinical practice, and the clinical manifestations are non-specific. Lung biopsy is helpful for diagnosis.
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