Omicron surge and the future of COVID-19 vaccinations

IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Medical Journal of Indonesia Pub Date : 2022-04-22 DOI:10.13181/mji.bc.226066
E. Burhan, Rizky Abi Rachmadi
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Abstract

The global surge of Omicron has caused significant concern. Omicron has caused new wave of infections in nations with adequate vaccine coverage. Omicron has around 30 mutations that are similar to the previous variant of concerns, possibly decreasing vaccine effectiveness (VE). Hence, the emergence of Omicron is predicted to be a significant public health challenge and may alter the future of COVID-19 vaccinations. Furthermore, other issues may affect vaccine policy in the future such as the never-ending vaccine inequity, waning immunity of current COVID-19 vaccines, decreasing VE against new emerging strains, and new findings regarding hybrid immunity. This literature review aimed to explore the possible steps forward using the most updated knowledge on COVID-19 vaccines and Omicron.
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奥密克戎激增与新冠肺炎疫苗接种的未来
奥密克戎在全球范围内的激增引起了极大的关注。奥密克戎在疫苗覆盖率足够的国家引发了新一波感染。奥密克戎有大约30个突变,与之前令人担忧的变种相似,可能会降低疫苗的有效性(VE)。因此,预计奥密克戎的出现将是一个重大的公共卫生挑战,并可能改变新冠肺炎疫苗接种的未来。此外,其他问题可能会影响未来的疫苗政策,如无休止的疫苗不公平、当前新冠肺炎疫苗的免疫力下降、针对新出现的毒株的VE下降,以及关于混合免疫的新发现。这篇文献综述旨在利用新冠肺炎疫苗和奥密克戎的最新知识,探索可能的前进步骤。
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来源期刊
Medical Journal of Indonesia
Medical Journal of Indonesia MEDICINE, GENERAL & INTERNAL-
CiteScore
1.00
自引率
20.00%
发文量
25
审稿时长
24 weeks
期刊介绍: Medical Journal of Indonesia is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health. This journal publishes original articles, reviews, and also interesting case reports. Brief communications containing short features of medicine, latest developments in diagnostic procedures, treatment, or other health issues that is important for the development of health care system are also acceptable. Letters and commentaries of our published articles are welcome.
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