The Efficacy of Ultrasound-Guided Bilateral Transversus Abdominal Plane (TAP) Block in Decreasing the Pain After Laparoscopic Cholecystectomy: A Randomized Clinical Trial

Lina May Osit, Joseph Joven Gammad, Olivia C. Flores
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Abstract

Introduction: Pain after laparoscopic cholecystectomy is complex in nature and several methods are performed to control it. Transversus Abdominis Plane (TAP) block has been used for postoperative pain for some abdominal surgeries. This study was designed to determine the analgesic efficacy of bilateral TAP block for patients undergoing Laparoscopic Cholecystectomy. Methods: Forty-two patients were randomized into 2 groups. Group 1 received TAP block using bupivacaine 0.25% (n=21), and group 2 received TAP block using saline. Before extubation, blocks were performed bilaterally. Tramadol IV was given for breakthrough pain for the first 24 hours. Pain scores using the Visual Analog Scale (VAS) at 0, 1, 2, 4 ,8 ,12, 24 hour-intervals, number of patient demand for Tramadol and patient satisfaction were collected. Results: Patients in the control group have higher VAS scores both during rest and on movement. However, pain was significantly reduced only on the 2nd hour at rest and on the 1st to 4th hours on movement among patients who received Bupivacaine 0.25% on TAP block. Furthermore, there was no significant difference in the requirement for rescue analgesics (p=0.1160) and the satisfaction rate (p=0.2849) between the two groups. Conclusion: TAP block is safe and improved postoperative analgesia in patients receiving laparoscopic cholecystectomy. But its additional analgesic effect in the presence of a dynamic multimodal pain-control regimen is probably rather small and need further investigation in laparoscopic cholecystectomy.
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超声引导下双侧经腹平面阻滞减轻腹腔镜胆囊切除术后疼痛的随机临床试验
腹腔镜胆囊切除术后的疼痛是复杂的,有几种方法可以控制疼痛。腹横平面阻滞(TAP)已被用于一些腹部手术的术后疼痛。本研究旨在确定双侧TAP阻滞对腹腔镜胆囊切除术患者的镇痛效果。方法:42例患者随机分为2组。组1采用0.25%布比卡因阻断TAP (n=21),组2采用生理盐水阻断TAP。拔管前,双侧进行阻滞。最初24小时给予曲马多IV治疗突破性疼痛。采用视觉模拟评分法(VAS)分别在0、1、2、4、8、12、24小时间隔进行疼痛评分、曲马多用药需求数和患者满意度。结果:对照组患者在休息和运动时的VAS评分均较高。然而,在接受0.25%布比卡因阻滞的患者中,疼痛仅在休息第2小时和运动第1至第4小时显著减轻。两组患者对抢救镇痛药的需求(p=0.1160)和满意率(p=0.2849)差异无统计学意义。结论:TAP阻滞在腹腔镜胆囊切除术患者中是安全的,可改善术后镇痛。但其在动态多模式疼痛控制方案下的额外镇痛效果可能相当小,需要在腹腔镜胆囊切除术中进一步研究。
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