Paving the way to environment-friendly greener anesthesia.

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-01 Epub Date: 2023-04-07 DOI:10.4103/joacp.joacp_283_22
Lal Dhar Mishra, Ankit Agarwal, Atul K Singh, Kamath Sriganesh
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Abstract

Health-care settings have an important responsibility toward environmental health and safety. The operating room is a major source of environmental pollution within a hospital. Inhalational agents and nitrous oxide are the commonly used gases during general anesthesia for surgeries, especially in the developing world. These greenhouse gases contribute adversely to the environmental health both inside the operating room and in the outside atmosphere. Impact of these anesthetic agents depends on the total consumption, characteristics of individual agents, and gas flows, with higher levels increasing the environmental adverse effects. The inimical impact of nitrous oxide is higher due to its longer atmospheric half-life and potential for destruction of the ozone layer. Anesthesiologist of today has a choice in the selection of anesthetic agents. Prudent decisions will help in mitigating environmental pollution and contributing positively to a greener planet. Therefore, a shift from inhalational to intravenous-based technique will reduce the carbon footprint of anesthetic agents and their impact on global climate. Propofol forms the mainstay of intravenous anesthesia technique and is a proven drug for anesthetic induction and maintenance. Anesthesiologists should appreciate growing concerns about the role of inhalational anesthetics on the environment and join the cause of environmental responsibility. In this narrative review, we revisit the pharmacological and pharmacokinetic considerations, clinical uses, and discuss the merits of propofol-based intravenous anesthesia over inhalational anesthesia in terms of environmental effects. Increased awareness about the environmental impact and adoption of newer, versatile, and user-friendly modalities of intravenous anesthesia administration will pave the way for greener anesthesia practice.

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为环境友好、更环保的麻醉铺平道路
医疗机构对环境健康和安全负有重要责任。手术室是医院环境污染的主要来源。吸入剂和氧化亚氮是手术全身麻醉时常用的气体,尤其是在发展中国家。这些温室气体对手术室内外的环境健康都有不利影响。这些麻醉剂的影响取决于总消耗量、单个麻醉剂的特性和气体流量,浓度越高,对环境的不利影响越大。一氧化二氮的有害影响更大,因为它在大气中的半衰期更长,有可能破坏臭氧层。当今的麻醉医师在选择麻醉剂时有多种选择。审慎的决定将有助于减轻环境污染,为建设绿色地球做出积极贡献。因此,从吸入式技术向静脉注射技术的转变将减少麻醉剂的碳足迹及其对全球气候的影响。丙泊酚是静脉麻醉技术的主要药物,也是一种行之有效的麻醉诱导和维持药物。麻醉医师应该了解人们日益关注吸入麻醉剂对环境的作用,并加入到对环境负责的事业中来。在这篇叙述性综述中,我们重温了药理学和药代动力学方面的考虑因素、临床用途,并讨论了基于异丙酚的静脉麻醉在环境影响方面优于吸入麻醉的情况。提高对环境影响的认识以及采用更新、多功能和用户友好的静脉麻醉给药方式将为更环保的麻醉实践铺平道路。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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