Clinical applications of esophageal stents

Mallory K. Wilson, Shamus R. Carr
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Abstract

Esophageal stents have been in surgical practice for over a century and continue to advance. Their use has led to changes in treatment paradigms and improved outcomes for a myriad of esophageal diseases. A variety of stents are used in the palliation of dysphagia in patients with malignant disease as well as part of a treatment plan in those with benign conditions. All stent placements begin with upper endoscopy in order to determine exact location of the pertinent pathology and use of a guidewire to set up for stent placement by the chosen technique. The type of stent chosen can vary based upon the etiology and presentation of each patient. In addition to stents that are commonly used today in management of patients, some of the newest developments in stent technology include 3D custom printed stents, biodegradable stents for benign strictures, or incorporating other therapeutic adjuncts to permit the slow-release of anti-cancer drugs. While complications during esophageal stent placement are rare, patients can experience bleeding or pain. These are generally self-limited. The most common complication is stent migration, which can be reduced with endoscopic fixation techniques. Much less common, but significantly more complex, is erosion through the esophagus. As surgical care continues to move towards less invasive approaches, endoscopic stent placement will continue to be a great option for numerous esophageal diseases. New opportunities for technological advancements are emerging that may further change current treatment algorithms for both malignant and benign pathologies. This may further give way to improved long-term outcomes or expansion of treatment options for patients.
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食管支架的临床应用
食管支架在外科实践中已经有一个多世纪的历史,并且还在继续发展。它们的使用改变了治疗模式,改善了无数食道疾病的治疗效果。各种支架用于缓解恶性疾病患者的吞咽困难,以及良性疾病患者的治疗计划的一部分。所有支架置入都从上腔镜检查开始,以确定相关病理的确切位置,并使用导丝根据所选技术设置支架置入。所选择的支架类型可以根据每个患者的病因和表现而有所不同。除了目前在患者管理中常用的支架外,支架技术的一些最新发展包括3D定制打印支架,用于良性狭窄的可生物降解支架,或结合其他治疗辅助物以允许抗癌药物缓慢释放。虽然食管支架置入期间的并发症很少见,但患者可能会出现出血或疼痛。这些通常是自我限制的。最常见的并发症是支架移位,这可以通过内镜固定技术来减少。不太常见,但明显更复杂的是食道糜烂。随着外科治疗不断向侵入性更小的方向发展,内镜下支架置入术将继续成为许多食道疾病的一个很好的选择。技术进步的新机会正在出现,可能进一步改变目前恶性和良性病理的治疗算法。这可能会进一步改善患者的长期预后或扩大治疗选择。
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