Multiple sclerosis in pregnancy. Treatment options and outcomes: a review

D. Cudalbă, N. Gică, G. Peltecu, R. Botezatu, A. Panaitescu
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Abstract

Background. Women are commonly diagnosed with multiple sclerosis during reproductive age. There is need for disease control management during pregnancy, taking into consideration potential maternal and fetal risks. This review article aims to summarize what is acknowledged so far regarding treatment options of multiple sclerosis and outcomes in pregnancy, providing up-to-date information. Methods. In order to write this review a comprehensive literature electronic search for journal articles and guidelines regarding multiple sclerosis during pregnancy was undertaken. Results and conclusion. Multiple sclerosis management in pregnancy is a challenging issue. The use of disease-modifying drugs has improved both the course of the disease and the attitude towards pregnancy in patients living with multiple sclerosis. Pregnancy appears to have a protective effect on disease activity, particularly during the third trimester.
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妊娠期多发性硬化症。治疗选择和结果:综述
背景女性通常在育龄期被诊断为多发性硬化症。需要在怀孕期间进行疾病控制管理,同时考虑到潜在的孕产妇和胎儿风险。这篇综述文章旨在总结迄今为止公认的多发性硬化症的治疗选择和妊娠结局,提供最新信息。方法。为了撰写这篇综述,对妊娠期多发性硬化症的期刊文章和指南进行了全面的文献电子检索。结果和结论。妊娠期多发性硬化症的管理是一个具有挑战性的问题。疾病改良药物的使用改善了多发性硬化症患者的病程和对妊娠的态度。怀孕似乎对疾病活动有保护作用,尤其是在妊娠晚期。
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来源期刊
CiteScore
0.40
自引率
0.00%
发文量
30
审稿时长
4 weeks
期刊介绍: ROMANIAN JOURNAL OF NEUROLOGY (Revista Română de Neurologie), the official journal of the Romanian Society of Neurology, was founded in 2001, being a prestigious scientific journal that provides a high quality in terms of scientific content, but also the editorial and graphic aspect, both through an impartial process of selection, evaluation and correction of articles (peer review procedure), as well as providing editorial, graphic and printing conditions at the highest level. In order to increase the scientific standards of the journal, special attention was paid to the improvement of the quality of the published materials. Guidance articles, clinical trials and case studies are structured in several sections: reviews, original articles, case reports, images in neurology. All articles are published entirely in English. A team of reputable medical professionals in the field of neurology is involved in a rigorous peer review process that complies with international ethics and quality rules in the academic world.
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