Platelet-rich fibrin therapy in the management of nonhealing trophic ulcers due to underlying leprous neuropathy.

Q3 Medicine Journal of Cutaneous and Aesthetic Surgery Pub Date : 2024-07-01 Epub Date: 2023-06-27 DOI:10.4103/JCAS.JCAS_192_22
Senkadhir Vendhan, Shekhar Neema, Biju Vasudevan, Lekshmipriya Krishnan, Vinay Gera
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Abstract

Autologous platelet-rich fibrin (PRF) therapy is beneficial in the treatment of nonhealing ulcers. We present a case series of nonhealing, trophic ulcers with underlying leprous neuropathy, treated successfully with PRF therapy. It was a prospective study, conducted in a tertiary care hospital in the western Maharashtra, India between April 2021 and March 2022. A total of 11 patients with 18 nonhealing trophic ulcers were included in the study and consisted of 8 men and 3 women. The patient's median age was 41 years (range, 33-68), the median size of the ulcers was 4 cm2 (range: 1-12 cm2), the median duration of ulcers was 20 weeks (16-30 weeks), and time to heal after starting treatment was 4 weeks (range: 1-8 weeks). PRF is an easy-to-use, simple, safe, effective, and economical treatment for the management of trophic ulcers.

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富含血小板的纤维蛋白治疗潜在麻风神经病变引起的营养性溃疡
自体富血小板纤维蛋白(PRF)疗法有利于治疗不愈合溃疡。我们介绍了一例采用 PRF 疗法成功治疗伴有潜在麻风神经病变的不愈合营养性溃疡的系列病例。这是一项前瞻性研究,于 2021 年 4 月至 2022 年 3 月期间在印度马哈拉施特拉邦西部的一家三级医院进行。研究共纳入了11名患有18处不愈合营养性溃疡的患者,其中男性8人,女性3人。患者年龄中位数为 41 岁(范围:33-68 岁),溃疡面积中位数为 4 平方厘米(范围:1-12 平方厘米),溃疡持续时间中位数为 20 周(16-30 周),开始治疗后痊愈时间为 4 周(范围:1-8 周)。PRF是一种易于使用、简单、安全、有效且经济的治疗营养性溃疡的方法。
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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
60
审稿时长
29 weeks
期刊介绍: The journal will cover aspects of Dermatosurgery and Aesthetic surgery, including cutaneous surgical procedures, lasers, light based treatments and aesthetic treatments. Authors of articles addressing topics such as skin tumours, pigmentary disorders, histopathology, diagnostic techniques, drugs, applications of cosmeceuticals surgical aspects, including pre and post procedural care are highly encouraged to submit with us. The journal also publishes articles on topics in allied specialities suh as plastic surgery, maxillofacial surgery vascular surgery, oculoplastic surgery etc. that are relevant to Dermatosurgery. The journal gives preference to clinically oriented studies over experimental and animal studies. The Journal would publish peer-reviewed Original Research Articles, Systematic reviews, Narrative Reviews, Case reports, Innovations and Debates. Letters to the editor, practice points, pearls in cutaneous and aesthetic surgery, quiz page, images, novel techniques, newer uses of instruments and video presentations and ethical aspects of cutaneous and aesthetic surgery are also invited.
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