Diabetes Mellitus and Recurrent Tako-Tsubo Syndrome

Abstract

Tako-tsubo syndrome or cardiomyopathy also referred to as transient apical ballooning syndrome, stress cardiomyopathy or broken heart syndrome is a well-recognized syndrome typically characterized by transient and reversible left ventricular dysfunction that develops in the setting of acute severe emotional or physical stress. Increased catecholamine levels have been proposed to play a central role in the pathogenesis of the disease, although the specific pathophysiology of this condition remains to be fully determined. At present, there have been few reports of Takotsubo cardiomyopathy associated with diabetes mellitus. In this report, we present a 3-years follow-up in a patient with previous multiple recurrences of Takotsubo triggered by diabetic ketoacidosis with resolution and full recovery after strict diabetic control.