{"title":"Calpain and oral cancer – A novel approach to detect cancer cell invasion","authors":"Sayani Shome, Shiladitya Sil","doi":"10.4103/ijds.ijds_77_21","DOIUrl":null,"url":null,"abstract":"Calpain is a Ca2+ dependent non-lysosomal cytosolic and mitochondrial cysteine protease found in tissue and organ specific manner in human being and in other mammals. It is observed to be an initiator for cancer cell propagation and invasion in Oral Squamous Cell Carcinoma (OSCC) and also a regulator of apoptosis. A concised review on this novice molecule is re-explored based on previous and ongoing studies in the following article.","PeriodicalId":56210,"journal":{"name":"Indian Journal of Dental Sciences","volume":"14 1","pages":"51 - 52"},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Dental Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/ijds.ijds_77_21","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Calpain is a Ca2+ dependent non-lysosomal cytosolic and mitochondrial cysteine protease found in tissue and organ specific manner in human being and in other mammals. It is observed to be an initiator for cancer cell propagation and invasion in Oral Squamous Cell Carcinoma (OSCC) and also a regulator of apoptosis. A concised review on this novice molecule is re-explored based on previous and ongoing studies in the following article.
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