The role of extracorporeal membrane oxygenation in thoracic surgery—a narrative review

Shanghai chest Pub Date : 2021-01-01 DOI:10.21037/shc-22-21
T. Eadington, Korah Oommen
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Abstract

Background and Objective: Thoracic surgical patients provide unique challenges which can make maintaining adequate ventilation difficult or impossible. Despite advances in anaesthetic technique there are situations where other methods must be employed. The aim of this review is to provide an overview of extracorporeal membrane oxygenation (ECMO) and how it can be utilised in thoracic surgical patients. Methods: Library searches of PubMed ® and EMBASE databases were carried out to identify literature for inclusion in this review. Timeframe for consideration was from origin to 5/1/22. No restrictions were made on the basis of language. Content and Findings: ECMO has traditionally been used in emergency settings to manage severe respiratory or haemodynamic failure refractory to conventional medical therapy. In recent years there has been an expansion in the use of this technology beyond these settings, and it is increasingly being used in a range of emergency and elective thoracic surgical patients. The configuration of the ECMO circuit, and it’s duration of use are determined by the clinical need. The use of ECMO is associated with significant complications therefore its use requires careful consideration by an experienced multidisciplinary team. Complications can be related to the underlying pathology and patient related factors, or due to circuit related factors and the duration of use. Conclusions: The use of ECMO in thoracic surgery is rare and thus the evidence base is limited. As its use in thoracic surgical patients continues to increase, there is clear need for randomised trials to demonstrate the benefit of this technology in this complex group of patients.
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体外膜氧合在胸外科手术中的作用综述
背景和目的:胸科手术患者面临着独特的挑战,这可能会使维持充分的通气变得困难或不可能。尽管麻醉技术取得了进步,但在某些情况下必须采用其他方法。本综述的目的是概述体外膜肺氧合(ECMO)及其在胸部手术患者中的应用。方法:对PubMed®和EMBASE数据库进行图书馆检索,以确定纳入本综述的文献。审议的时间范围从最初到2022年5月1日。没有对语言作出任何限制。内容和发现:ECMO传统上用于急救环境,以管理传统药物治疗难以治疗的严重呼吸或血液动力学衰竭。近年来,这项技术的使用范围已经扩大到这些环境之外,并且越来越多地用于一系列急诊和选择性胸外科患者。ECMO电路的配置和使用时间由临床需要决定。ECMO的使用与严重并发症有关,因此其使用需要经验丰富的多学科团队仔细考虑。并发症可能与潜在的病理学和患者相关因素有关,也可能与电路相关因素和使用持续时间有关。结论:ECMO在胸部手术中的应用是罕见的,因此证据基础是有限的。随着它在胸部手术患者中的使用不断增加,显然需要进行随机试验来证明这项技术在这一复杂患者群体中的益处。
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