Cerebral border zone infarctions: An etiologic study.

IF 0.5 Q4 CLINICAL NEUROLOGY Current Journal of Neurology Pub Date : 2022-01-05 DOI:10.18502/cjn.v21i1.9353
Mazyar Hashemilar, Parla Tohidi, Nasrin Forghani, Elyar Sadeghi-Hokmabadi, Ehsan Sharifipour
{"title":"Cerebral border zone infarctions: An etiologic study.","authors":"Mazyar Hashemilar, Parla Tohidi, Nasrin Forghani, Elyar Sadeghi-Hokmabadi, Ehsan Sharifipour","doi":"10.18502/cjn.v21i1.9353","DOIUrl":null,"url":null,"abstract":"<p><p><b>Background:</b> Cerebral border zone infarctions (BZIs) are a subtype of acute ischemic stroke that occur at the junction between two major cerebral arterial territories. Internal and external BZIs are defined based on the known patterns in brain magnetic resonance imaging (MRI). However, the etiology and pathophysiology of these two types of BZI are still debated. This study aimed to determine the etiologic differences of two types of BZI to guide tailor appropriate treatment strategies for these patients. <b>Methods:</b> In this prospective study, patients with BZIs were enrolled from patients with acute ischemic stroke admitted to the hospitals affiliated with Tabriz University of Medical Sciences, Tabriz, Iran, from 2017 to 2019. Appropriate clinical and laboratory workups were applied to determine possible etiologies of ischemic stroke according to the Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification system. <b>Results:</b> The study included 106 patients with BZI, 53 patients in each group. Both types of BZI were more frequent in males. However, there was no significant difference between the two types concerning sex, age, and profile of major stroke risk factors. The results showed no correlation between the type of BZI and hemodynamic factors (P = 0.086). However, large artery atherosclerosis (LAA) was the most frequent etiology within each subtype of BZI; LAA in internal (P = 0.016) and cardioembolism (P = 0.046) in external BZI were more frequent etiologic subtypes of cerebral infarction. <b>Conclusion:</b> LAA might be the most common etiology for internal and external cerebral BZIs. Cardioembolism might have a more important etiologic role in the external subtype.</p>","PeriodicalId":40077,"journal":{"name":"Current Journal of Neurology","volume":"21 1","pages":"1-6"},"PeriodicalIF":0.5000,"publicationDate":"2022-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527865/pdf/","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Journal of Neurology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18502/cjn.v21i1.9353","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 1

Abstract

Background: Cerebral border zone infarctions (BZIs) are a subtype of acute ischemic stroke that occur at the junction between two major cerebral arterial territories. Internal and external BZIs are defined based on the known patterns in brain magnetic resonance imaging (MRI). However, the etiology and pathophysiology of these two types of BZI are still debated. This study aimed to determine the etiologic differences of two types of BZI to guide tailor appropriate treatment strategies for these patients. Methods: In this prospective study, patients with BZIs were enrolled from patients with acute ischemic stroke admitted to the hospitals affiliated with Tabriz University of Medical Sciences, Tabriz, Iran, from 2017 to 2019. Appropriate clinical and laboratory workups were applied to determine possible etiologies of ischemic stroke according to the Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification system. Results: The study included 106 patients with BZI, 53 patients in each group. Both types of BZI were more frequent in males. However, there was no significant difference between the two types concerning sex, age, and profile of major stroke risk factors. The results showed no correlation between the type of BZI and hemodynamic factors (P = 0.086). However, large artery atherosclerosis (LAA) was the most frequent etiology within each subtype of BZI; LAA in internal (P = 0.016) and cardioembolism (P = 0.046) in external BZI were more frequent etiologic subtypes of cerebral infarction. Conclusion: LAA might be the most common etiology for internal and external cerebral BZIs. Cardioembolism might have a more important etiologic role in the external subtype.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
脑边界区梗死的病因研究
背景:脑边界区梗死(BZIs)是发生在两个主要脑动脉区域交界处的急性缺血性中风的一种亚型。内部和外部BZI是基于脑磁共振成像(MRI)中的已知模式来定义的。然而,这两种类型的BZI的病因和病理生理学仍存在争议。本研究旨在确定两种类型BZI的病因差异,以指导为这些患者制定适当的治疗策略。方法:在这项前瞻性研究中,BZIs患者来自2017年至2019年入住伊朗大不里士医学科学大学附属医院的急性缺血性中风患者。根据Org 10172在急性卒中治疗中的试验(TOAST)分类系统,应用适当的临床和实验室检查来确定缺血性卒中的可能病因。结果:本研究包括106例BZI患者,每组53例。两种类型的BZI在男性中更常见。然而,这两种类型在性别、年龄和主要中风危险因素方面没有显著差异。结果表明,BZI的类型与血液动力学因素之间无相关性(P=0.086),但大动脉动脉粥样硬化(LAA)是BZI各亚型中最常见的病因;脑梗塞的病因亚型中,内侧LAA(P=0.016)和外侧BZI的心栓塞(P=0.046)更常见。结论:LAA可能是内外脑BZIs最常见的病因。心脏栓塞可能在外部亚型中具有更重要的病因作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Current Journal of Neurology
Current Journal of Neurology CLINICAL NEUROLOGY-
CiteScore
0.80
自引率
14.30%
发文量
30
审稿时长
12 weeks
期刊最新文献
Assessment of median nerve with magnetic resonance neurography in cases with carpal tunnel syndrome and controls. Diagnostic potential of lncRNAs-ANRIL and MIAT in the blood of patients with cerebral venous thrombosis. Investigation of pregnancy tendency, reproductive characteristics, and disability in women with multiple sclerosis: A secondary data analysis of the national registry in Iran. Mass-like presentation of primary angiitis of the central nervous system: A clinical note. Meralgia paresthetica treated with temporary peripheral nerve stimulation.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1