K. Patel, Asish Vijayaraghavan, Syam Krishnan, D. Puthenveedu, A. Cherian
{"title":"Hemifacial spasm resulting from vertebrobasilar dolichoectasia in three siblings: A case report","authors":"K. Patel, Asish Vijayaraghavan, Syam Krishnan, D. Puthenveedu, A. Cherian","doi":"10.4103/aomd.aomd_13_22","DOIUrl":null,"url":null,"abstract":"Hemifacial spasm is a common peripheral movement disorder that usually results from neurovascular conflict involving the facial nerve motor root exit zone. Although it is a sporadic disease, some cases of familial clustering have been reported. In this case report, we present a case of familial occurrence of hemifacial spasm with dolichoectasia of the vertebrobasilar system in three siblings. The patients responded well to botulinum toxin therapy. A genetic mechanism predisposing them to vascular abnormalities is likely to be responsible for the clinical–radiological picture in our patients.","PeriodicalId":7973,"journal":{"name":"Annals of Movement Disorders","volume":"5 1","pages":"202 - 204"},"PeriodicalIF":0.0000,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Movement Disorders","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/aomd.aomd_13_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Hemifacial spasm is a common peripheral movement disorder that usually results from neurovascular conflict involving the facial nerve motor root exit zone. Although it is a sporadic disease, some cases of familial clustering have been reported. In this case report, we present a case of familial occurrence of hemifacial spasm with dolichoectasia of the vertebrobasilar system in three siblings. The patients responded well to botulinum toxin therapy. A genetic mechanism predisposing them to vascular abnormalities is likely to be responsible for the clinical–radiological picture in our patients.