Nivolumab Induced Acute Pancreatitis and Hyperbilirubinemia

Bhatia Unnati, Bajaj Suryansh, Gandhi Darshan, Bajaj Divyansh
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Abstract

Immune checkpoint inhibitors (ICIs) are a novel treatment modality that is quickly becoming the standard of care for the management of a multitude of neoplasms. While immunomodulation is a promising approach, it also carries a risk of immune-related adverse effects (irAEs). Nivolumab is an FDA-approved anti-programmed death-1 (anti-PD-1) checkpoint inhibitor. Nivolumab-induced, immune-related pancreatitis, and hyperbilirubinemia are rare but clinically significant examples of irAEs. Early recognition and prompt management of these conditions are critically important to ensure a better prognosis and prevention of subsequent complications. We report a of
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尼沃单抗诱导的急性胰腺炎和高胆红素血症
免疫检查点抑制剂(ICIs)是一种新的治疗方式,正迅速成为多种肿瘤治疗的标准治疗方法。虽然免疫调节是一种很有前途的方法,但它也存在免疫相关不良反应(irAEs)的风险。Nivolumab是fda批准的抗程序性死亡-1 (anti-PD-1)检查点抑制剂。尼沃鲁单抗引起的免疫相关性胰腺炎和高胆红素血症是罕见但具有临床意义的irae病例。早期识别和及时处理这些疾病对于确保更好的预后和预防随后的并发症至关重要。我们报告了
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