Hepatic focal nodular hyperplasia in a five-year-old healthy boy: A case report and literature review

IF 0.2 Q4 GASTROENTEROLOGY & HEPATOLOGY International Journal of Hepatobiliary and Pancreatic Diseases Pub Date : 2021-08-27 DOI:10.5348/100095z04aa2021cr
A. Alfayez, Helayel Almodhaiberi, H. Al Hussaini, Ibrahim Alhasan, Abdullah A Algarni, Tharaa Y. Takrouni
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引用次数: 1

Abstract

Introduction: Focal nodular hyperplasia is unusually seen in a pediatric age group, with few reported cases in the literature. We report the case of a 5-year-old boy not known to have medical illnesses, who was found to have a liver mass, underwent right trisectionectomy. The purpose of this report is to familiarize the healthcare community with similar events, review the literature, and discuss recommendations for future similar cases. Case Report: A case of focal nodular hyperplasia (FNH) in a 5-year-old healthy boy who was found to have a huge liver lesion on ultrasound imaging due to a vague abdominal pain and distension. The patient underwent surgical excision of the mass due to abdominal pain, distension, and atypical features of FNH in radiological examinations. Histopathological analysis revealed a focal nodular hyperplasia. Conclusion: Focal nodular hyperplasia considered a benign lesion that has no malignant transformation. The presenting symptoms are variable, usually asymptomatic. Laboratory tests have of little significance. Imaging modalities mainly ultrasound scan initially then magnetic resonance imaging (MRI) are useful to obtain more accurate characteristic features of the lesion. Uncertain diagnostic lesion needs to be biopsied and examined under microscopy. Confirming the diagnosis will follow an acceptable conservative management approach. Surgical resection is the preferred method in uncertain, questionable, or atypical features observed in radiological imaging.
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5岁健康男孩肝局灶性结节增生1例报告及文献复习
局灶性结节增生在儿童年龄组中很少见,文献中很少报道。我们报告的情况下,一个5岁的男孩不知道有医学疾病,谁被发现有一个肝脏肿块,接受了右三节切除术。本报告的目的是使医疗界熟悉类似的事件,回顾文献,并讨论对未来类似病例的建议。病例报告:1例5岁健康男孩的局灶性结节性增生(FNH),在超声检查中发现有一个巨大的肝脏病变,由于模糊的腹痛和腹胀。由于腹痛、腹胀和FNH在放射检查中的不典型特征,患者接受了手术切除肿块。组织病理学分析显示局灶性结节性增生。结论:局灶性结节增生为良性病变,无恶性转化。表现出的症状多种多样,通常无症状。实验室检查没有什么意义。成像方式主要是超声扫描,然后磁共振成像(MRI)有助于获得更准确的病变特征。诊断不明确的病变需要活检和显微镜检查。确诊将遵循可接受的保守治疗方法。在放射影像上观察到不确定、可疑或不典型的特征时,手术切除是首选方法。
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