Aachak M, Brarou H, B. H, Jeddou I, A. T, E. F, M. Y, Reda K, Oubaaz A
{"title":"A Case of Bilateral Pseudo Papilledema Revealing a Leber’s Hereditary Optic Neuropathy","authors":"Aachak M, Brarou H, B. H, Jeddou I, A. T, E. F, M. Y, Reda K, Oubaaz A","doi":"10.26420/austinjclinopthalmol.2022.1128","DOIUrl":null,"url":null,"abstract":"Leber Hereditary Optic Neuropathy (LHON) is a mitochondrial disease caused by mutations in mitochondrial DNA affecting the respiratory complex I and leading to the death of retinal ganglion cells (RGCs) [1]. It is characterized by sudden onset and usually severe bilateral loss of central vision, predominantly in young men [2]. The risk of vision loss is 50% among men and 10% among women who carry LHON primary mutations in the mitochondrial DNA [3]. We report an atypic case of LHON in a young 11 years old girl.","PeriodicalId":90447,"journal":{"name":"Austin journal of clinical ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Austin journal of clinical ophthalmology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26420/austinjclinopthalmol.2022.1128","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Leber Hereditary Optic Neuropathy (LHON) is a mitochondrial disease caused by mutations in mitochondrial DNA affecting the respiratory complex I and leading to the death of retinal ganglion cells (RGCs) [1]. It is characterized by sudden onset and usually severe bilateral loss of central vision, predominantly in young men [2]. The risk of vision loss is 50% among men and 10% among women who carry LHON primary mutations in the mitochondrial DNA [3]. We report an atypic case of LHON in a young 11 years old girl.