{"title":"Two Cases of Single-fingernail Fungal Leukonychia with\nVarying Manifestations","authors":"Su Min Lee, S. Yun, J. Lee","doi":"10.17966/jmi.2022.27.4.82","DOIUrl":null,"url":null,"abstract":"Leukonychia is the white discoloration of the nail, and it is a common chromatic abnormality of the nail. Leukonychia can be caused by various systemic conditions; however, a fungal infection is also a probable cause. Herein, we report two cases that presented with varying patterns of single-nail leukonychia and were diagnosed with fungal leukonychia based on potassium hydroxide (KOH) examination and fungal culture. A 59-year-old man presented with asymptomatic complete whitish discoloration of the right fourth fingernail. KOH examination revealed many septate hyphae, and Trichophyton rubrum was identified through fungal culture and 18S rRNA sequencing. A 32-year-old man presented with asymptomatic longitudinal ridges and pitting with partial whitish discoloration of the second left fingernail persistent for 5 years. KOH examination revealed many short hyphae, and Scedosporium species was identified on fungal culture.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Mycology and Infection","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17966/jmi.2022.27.4.82","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Leukonychia is the white discoloration of the nail, and it is a common chromatic abnormality of the nail. Leukonychia can be caused by various systemic conditions; however, a fungal infection is also a probable cause. Herein, we report two cases that presented with varying patterns of single-nail leukonychia and were diagnosed with fungal leukonychia based on potassium hydroxide (KOH) examination and fungal culture. A 59-year-old man presented with asymptomatic complete whitish discoloration of the right fourth fingernail. KOH examination revealed many septate hyphae, and Trichophyton rubrum was identified through fungal culture and 18S rRNA sequencing. A 32-year-old man presented with asymptomatic longitudinal ridges and pitting with partial whitish discoloration of the second left fingernail persistent for 5 years. KOH examination revealed many short hyphae, and Scedosporium species was identified on fungal culture.
期刊介绍：
The Journal of mycology and infection (Acronym: JMI, Abbreviation: J Mycol Infect) aims to publish articles of exceptional interests in the field of medical mycology. The journal originally was launched in 1996 as the Korean Journal of Medical Mycology and has reformed into the current state beginning on March of 2018. The contents of the journal should elucidate important microbiological fundamentals and provide qualitative insights to respective clinical aspects. JMI underlines the submission of novel findings and studies in clinical mycology that are enriched by analyses achieved through investigative methods. The journal should be of general interests to the scientific communities at large and should provide medical societies with advanced breadth and depth of mycological expertise. In addition, the journal supplements infectious diseases in adjunct to the field of mycology to address a well-rounded understanding of infectious disorders. The Journal of mycology and infection, which is issued quarterly, in March, June, September and December each year, published in English. The scope of the Journal of mycology and infection includes invited reviews, original articles, case reports, letter to the editor, and images in mycology. The journal is compliant to peer-review/open access and all articles undergo rigorous reviewing processes by our internationally acknowledged team of editorial boards. The articles directed to publication should encompass in-depth materials that employ scholastic values of mycology and various infectious diseases. Articles responding to critical methodology and outcomes which have potential to enhance better understanding of mycology and infectious diseases are also suitable for publication.
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