Establishment of model for predicting mortality risk after abdominal surgery using preoperative indices based on different machine learning algorithms

Hong-Yu Zhi, Mengyue Gu, Yu-jie Li, Zhi-Yong Yang, Kunhua Zhong, Yuwen Chen, Ju Zhang, B. Yi, K. Lu
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Abstract

Objective To establish the model for predicting the mortality risk after abdominal surgery using preoperative indices based on different machine learning algorithms. Methods Fifty patients died after abdominal surgery with general anesthesia from June 2015 to December 2018 in our hospital were enrolled in the study.Based on the types of surgery and age of dead patients, 150 patients who were discharged from hospital upon recovery postoperatively were randomly selected from our database as control cases with a ratio of 1∶3.The total dataset of 200 patients was randomly divided into training dataset (n=140) and testing dataset (n=60). Preoperative indices (each index of baseline characteristics, each index of anesthesia interview information and indices of preoperative examination) were used to develop the model for predicting the mortality risk after abdominal surgery based on four machine learning algorithms AdaBoost, GBDT, LR, and SVM, and the model was evaluated in the testing dataset. Results The area under the receiver operating characteristic curves of models developed using preoperative index based on AdaBoost, GBDT, LR, and SVM for predicting the postoperative mortality risk were 0.796, 0.794, 0.846 and 0.781, respectively.There were no significant differences in area under the receiver operating characteristic curves among different models (P>0.05). Conclusion The model for predicting mortality risk after abdominal surgery using preoperative indicators based on different machine learning algorithms is successfully established. Key words: Artificial intelligence; Machine learning; Forecasting; Death; Postoperative complications
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基于不同机器学习算法的术前指标腹部手术死亡风险预测模型的建立
目的建立基于不同机器学习算法的术前指标预测腹部手术后死亡风险的模型。方法选取2015年6月至2018年12月我院收治的50例腹部全麻手术死亡患者。根据手术类型和死亡患者的年龄,从数据库中随机抽取术后康复出院患者150例作为对照病例,比例为1∶3。200例患者的总数据集随机分为训练数据集(n=140)和测试数据集(n=60)。采用术前指标(基线特征各指标、麻醉访谈信息各指标、术前检查指标),基于AdaBoost、GBDT、LR、SVM四种机器学习算法建立腹部手术后死亡风险预测模型,并在测试数据集中对模型进行评估。结果基于AdaBoost、GBDT、LR和SVM的术前指数模型预测术后死亡风险的受试者工作特征曲线下面积分别为0.796、0.794、0.846和0.781。不同模型的受试者工作特征曲线下面积差异无统计学意义(P < 0.05)。结论成功建立了基于不同机器学习算法的术前指标预测腹部手术后死亡风险模型。关键词:人工智能;机器学习;预测;死亡;术后并发症
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中华麻醉学杂志
中华麻醉学杂志 Medicine-Anesthesiology and Pain Medicine
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