Physicochemical Analysis of Dental and Household Hypochlorites

Michele Méndez Velázquez
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Abstract

Aim: Sodium hypochlorite is the most common solution in the Endodontics field, however, NaOCl concentrations of commercial brands which are prepared for this purpose differ from their actual concentration. The aim of this study was to compare the physicochemical properties of dental and household hypochlorites. Materials and Methods: The solutions were divided in the following groups: Control: Clorarex 6%, Group 1: Viarzoni-T 5.25%, Group 2: Endo Chlord 3%, Group 3: Chlor- XTRA 6%, Group 4: Viarzoni-T (diluted from 5.25%), Group 5: Cloralex (diluted from 6%), Group 6: Chlor- Xtra (diluted from 6%). pH and temperature were measured by means of potentiometer, dilution test was performed using bovine tissue and exposed to each solution. For cytotoxicity assay, erythrocytes were exposed to each solution and stained with Sternheimer-Malbin solution. Results: Dissolution times showed a significant difference since the shortest time was Cloralex (6.6 ± 2.09). The solution with the highest alkalinity in the original concentration was Endo Chlord for dental use (11.7 ± 2.2). The solution with the highest alkalinity in the original concentration was Endo Chlord for dental use (11.7 ± 2.2) but it also was the solution with less cytotoxicity. Conclusion: Viarzoni-T was the only solution without any dissolving capacity, Cloralex, ChorlXtra and EndoChlord were capable of dissolving bovine pulp tissue effectively, reducing their concentration of Cloralex and ChlorXtra did not reduce the pH, but all solutions showed a cytotoxic effect on erythrocites.
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牙科和家用次氯酸盐的理化分析
目的:次氯酸钠是牙髓学领域最常见的溶液,然而,为此目的而制备的商业品牌的NaOCl浓度与其实际浓度不同。本研究的目的是比较牙科次氯酸盐和家用次氯酸盐的理化性质。材料与方法:将溶液分为以下组:对照组:Clorarex 6%,组1:Viarzoni-T 5.25%,组2:Endo Chlord 3%,组3:Chlor- XTRA 6%,组4:Viarzoni-T(以5.25%稀释),组5:Cloralex(以6%稀释),组6:Chlor- XTRA(以6%稀释)。用电位器测量pH值和温度,用牛组织暴露于每种溶液中进行稀释试验。细胞毒性试验中,将红细胞暴露于每种溶液中,并用施特恩海默-马尔宾溶液染色。结果:溶出时间差异有统计学意义,以Cloralex最短(6.6±2.09);原浓度碱度最高的是牙科用远藤氯碱(11.7±2.2)。原浓度下碱度最高的是牙科用远藤氯碱(11.7±2.2),但也是细胞毒性较小的溶液。结论:Viarzoni-T是唯一没有溶解能力的溶液,Cloralex、ChorlXtra和EndoChlord能有效溶解牛牙髓组织,降低Cloralex和ChlorXtra的浓度不降低pH,但所有溶液都对红细胞有细胞毒性作用。
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