Inf-Net: Automatic COVID-19 Lung Infection Segmentation From CT Images

IF 8.9 1区 医学 Q1 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS IEEE Transactions on Medical Imaging Pub Date : 2020-04-22 DOI:10.1101/2020.04.22.20074948
Deng-Ping Fan, Tao Zhou, Ge-Peng Ji, Yi Zhou, Geng Chen, H. Fu, Jianbing Shen, Ling Shao
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引用次数: 774

Abstract

Coronavirus Disease 2019 (COVID-19) spread globally in early 2020, causing the world to face an existential health crisis. Automated detection of lung infections from computed tomography (CT) images offers a great potential to augment the traditional healthcare strategy for tackling COVID-19. However, segmenting infected regions from CT slices faces several challenges, including high variation in infection characteristics, and low intensity contrast between infections and normal tissues. Further, collecting a large amount of data is impractical within a short time period, inhibiting the training of a deep model. To address these challenges, a novel COVID-19 Lung Infection Segmentation Deep Network (Inf-Net) is proposed to automatically identify infected regions from chest CT slices. In our Inf-Net, a parallel partial decoder is used to aggregate the high-level features and generate a global map. Then, the implicit reverse attention and explicit edge-attention are utilized to model the boundaries and enhance the representations. Moreover, to alleviate the shortage of labeled data, we present a semi-supervised segmentation framework based on a randomly selected propagation strategy, which only requires a few labeled images and leverages primarily unlabeled data. Our semi-supervised framework can improve the learning ability and achieve a higher performance. Extensive experiments on our COVID-SemiSeg and real CT volumes demonstrate that the proposed Inf-Net outperforms most cutting-edge segmentation models and advances the state-of-the-art performance.
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nf- net:从CT图像自动分割COVID-19肺部感染
2020年初,2019冠状病毒病(新冠肺炎)在全球蔓延,导致世界面临生存健康危机。通过计算机断层扫描(CT)图像自动检测肺部感染,为加强应对新冠肺炎的传统医疗策略提供了巨大潜力。然而,从CT切片中分割感染区域面临着一些挑战,包括感染特征的高度变异,以及感染与正常组织之间的低强度对比。此外,在短时间内收集大量数据是不切实际的,这阻碍了深度模型的训练。为了应对这些挑战,提出了一种新的新冠肺炎肺部感染分割深度网络(Inf-Net),用于从胸部CT切片中自动识别感染区域。在我们的Inf-Net中,使用并行部分解码器来聚合高级特征并生成全局映射。然后,利用隐式反向注意力和显式边缘注意力对边界进行建模并增强表示。此外,为了缓解标记数据的短缺,我们提出了一种基于随机选择的传播策略的半监督分割框架,该框架只需要少量标记图像,并主要利用未标记数据。我们的半监督框架可以提高学习能力并获得更高的性能。在我们的COVID-SemiSeg和真实CT体积上进行的大量实验表明,所提出的Inf-Net优于最先进的分割模型,并提高了最先进的性能。
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来源期刊
IEEE Transactions on Medical Imaging
IEEE Transactions on Medical Imaging 医学-成像科学与照相技术
CiteScore
21.80
自引率
5.70%
发文量
637
审稿时长
5.6 months
期刊介绍: The IEEE Transactions on Medical Imaging (T-MI) is a journal that welcomes the submission of manuscripts focusing on various aspects of medical imaging. The journal encourages the exploration of body structure, morphology, and function through different imaging techniques, including ultrasound, X-rays, magnetic resonance, radionuclides, microwaves, and optical methods. It also promotes contributions related to cell and molecular imaging, as well as all forms of microscopy. T-MI publishes original research papers that cover a wide range of topics, including but not limited to novel acquisition techniques, medical image processing and analysis, visualization and performance, pattern recognition, machine learning, and other related methods. The journal particularly encourages highly technical studies that offer new perspectives. By emphasizing the unification of medicine, biology, and imaging, T-MI seeks to bridge the gap between instrumentation, hardware, software, mathematics, physics, biology, and medicine by introducing new analysis methods. While the journal welcomes strong application papers that describe novel methods, it directs papers that focus solely on important applications using medically adopted or well-established methods without significant innovation in methodology to other journals. T-MI is indexed in Pubmed® and Medline®, which are products of the United States National Library of Medicine.
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