Primary intraosseous squamous cell carcinoma presenting as lytic lesion in mandible: Common presentation of an uncommon illness

Abstract

Squamous cell carcinomas (SCCs) occurring in the bones are largely metastatic in nature and primary intraosseous squamous cell carcinomas (PIOSCCs) are extremely rare. They tend to involve skull bones more frequently than the other bones. We present the case of a 52-year-old male, presenting with pain in the lower jaw, which was diagnosed with PIOSCC on histopathology.