STUDIES ON LIPID PROFILE AND LEVELS OF SOME SEX HORMONES IN SUBJECTS WITH PROSTATE CANCER

N. Constance, Ikaraoha Chidebere, A. Oluchi, Udeoha Uzodinna Augustine
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Abstract

Studies on lipid profile and levels of some sex hormones in subjects with prostate cancer were evaluated using standard methods. Two hundred volunteer subjects were recruited for the study. Results obtained for lipid profile showed significant (p<0.05) increase in levels of cholesterol, triglycerides, and LDL-cholesterol in test subjects when compared to control subjects. Levels of testosterone and prolactin were insignificantly (p>0.05) affected in test subjects against the control subjects. When the indices were considered along age groups A and B of this study, younger adult males between the age group of 40-58 years had increased cholesterol, triglycerides, and LDL-cholesterol while levels of prostate-specific antigen and sex hormone binding globulin were significantly higher in group B when compared to group A. These could be how they vary with respect to prostate cancer situation. This study has evaluated the lipid profile and levels of some sex hormones in subjects with prostate cancer.
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前列腺癌患者血脂及某些性激素水平的研究
采用标准方法对癌症前列腺受试者的脂质状况和某些性激素水平的研究进行评估。这项研究招募了200名志愿者。所获得的脂质图谱结果显示,与对照受试者相比,受试者受到显著影响(p0.05)。当根据本研究的年龄组A和B考虑这些指标时,40-58岁年龄组的年轻成年男性胆固醇、甘油三酯和低密度脂蛋白胆固醇增加,而与A组相比,B组的前列腺特异性抗原和性激素结合球蛋白水平显著更高。这些可能是它们随前列腺癌症情况而变化的方式。本研究评估了癌症前列腺患者的血脂状况和某些性激素水平。
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