Evaluation of Predicting the Value of the Reticulocyte Hemoglobin Equivalent for Iron Deficiency in Chronic Kidney Disease Patients

Q4 Medicine Nephro-urology Monthly Pub Date : 2022-05-11 DOI:10.5812/numonthly-121289
Kien Nguyen Trung, Hung Ta Viet, Hanh Nguyen Thi Hien, Van Nguyen Khanh, Tuyen Thai Danh, Thang Le Viet
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Abstract

Background: Iron management is essential for anemia treatment in chronic kidney disease. The reticulocyte hemoglobin equivalent (RET-He) is a reticulocyte parameter that reflects hemoglobin synthesis of newly formed erythrocytes in the bone marrow in real-time. Objectives: This study aims to evaluate the role of reticulocyte hemoglobin equivalent (RET-He) in predicting iron deficiency in chronic kidney disease (CKD) patients. Methods: Following a descriptive cross-sectional observational design, this study was conducted on 131 adult patients with CKD stages 3 - 5. Laboratory indices, including complete blood count, some biochemical indices, iron status, and reticulocyte indices (including RET-He), were measured. Iron deficiency (ID) was defined as TSAT < 20%, where serum ferritin level > 100 ng/mL was defined as functional ID, while serum ferritin level
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网状细胞血红蛋白当量对慢性肾脏病患者缺铁预测价值的评价
背景:铁管理对慢性肾脏疾病贫血治疗至关重要。网织红细胞血红蛋白当量(RET-He)是实时反映骨髓中新形成红细胞血红蛋白合成的网织红细胞参数。目的:本研究旨在评估网织红细胞血红蛋白当量(RET-He)在预测慢性肾脏疾病(CKD)患者缺铁中的作用。方法:本研究采用描述性横断面观察设计,对131例CKD 3 - 5期成年患者进行了研究。检测实验室指标,包括全血细胞计数、部分生化指标、铁状态、网织红细胞指标(包括RET-He)。铁缺乏(ID)定义为TSAT < 20%,其中血清铁蛋白水平> 100 ng/mL定义为功能性ID,而血清铁蛋白水平> 100 ng/mL定义为功能性ID
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来源期刊
Nephro-urology Monthly
Nephro-urology Monthly Medicine-Urology
CiteScore
0.40
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0.00%
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26
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