Matthew Adams D.O. , William Lainhart Ph.D., D(ABMM)
{"title":"A Review of Diagnostics for Coccidiomycosis","authors":"Matthew Adams D.O. , William Lainhart Ph.D., D(ABMM)","doi":"10.1016/j.clinmicnews.2021.07.003","DOIUrl":null,"url":null,"abstract":"<div><p><span>Coccidiomycosis<span> is an endemic mycosis that is caused by the dimorphic fungal organisms </span></span><em>Coccidoides immitis</em> and <em>C. posadasii</em><span>. Patients with coccidiomycosis often present for care with community-acquired pneumonia-like illness, and unfortunately, this diagnosis is not commonly at the top of a clinician’s differential, even in areas of endemicity. This review examines the various assays that can be used to diagnose infection with </span><span><em>Coccidioides</em></span><span> spp., including discussion of the performance and interpretation of serological assays, molecular diagnostics, and fungal culture. Additionally, the use of alternative, non-coccidioidal biomarkers to support the diagnosis are discussed.</span></p></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.clinmicnews.2021.07.003","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Microbiology Newsletter","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0196439921000489","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 3
Abstract
Coccidiomycosis is an endemic mycosis that is caused by the dimorphic fungal organisms Coccidoides immitis and C. posadasii. Patients with coccidiomycosis often present for care with community-acquired pneumonia-like illness, and unfortunately, this diagnosis is not commonly at the top of a clinician’s differential, even in areas of endemicity. This review examines the various assays that can be used to diagnose infection with Coccidioides spp., including discussion of the performance and interpretation of serological assays, molecular diagnostics, and fungal culture. Additionally, the use of alternative, non-coccidioidal biomarkers to support the diagnosis are discussed.
期刊介绍：
Highly respected for its ability to keep pace with advances in this fast moving field, Clinical Microbiology Newsletter has quickly become a “benchmark” for anyone in the lab. Twice a month the newsletter reports on changes that affect your work, ranging from articles on new diagnostic techniques, to surveys of how readers handle blood cultures, to editorials questioning common procedures and suggesting new ones.
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