C. Zhang, Yu-Xuan Ye, Dan-Ting Li, Si-Yu Zhang, Z. Shen
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引用次数: 0
Abstract
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
In this study, we report a de novo assembly of the chromosome-level WBPH genome with characterized sex chromosomes using third-generation sequencing technologies, Hi-C data and full-length transcripts, and provide a dense landscape of sex-specific transcriptome.
We generated a high-quality chromosome-level assembly with a contig N50 of 2.20 Mb and a scaffold N50 of 45.25 Mb. Fourteen autosomes and one X chromosomes were identified. More than 99.5% of the assembled bases located on the 15 chromosomes. 95.9% of the BUSCO complete genes were detected in the final assembly and 16,880 genes were annotated.
The integrated genome, definite sex chromosomes, comprehensive transcriptome profiles, high efficiency of RNA interference and short life cycle substantially made WBPH an efficient research object for functional genomics.
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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