Association of ATP-Binding Cassette Transporter A1 G1051A Polymorphism with Type 2 Diabetes, Lipids and Coronary Artery Disease in Tunisian Population

C. Raja, Mehri Sounira, Beizig Nadia, Ben Ayed Nadia, Hammami Sonia, Ben Hamda Kholdoun, Hammami Mohamed
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引用次数: 1

Abstract

Background: ATP-binding cassette transporter A1 (ABCA1) plays a key role in lipoprotein metabolism. This metabolism is perturbated in type 2 diabetes, and was associated with coronary artery disease (CAD). Thus, we aim to study the association between ABCA1 polymorphism and diabetes and the possibility to develop coronary artery disease in those patients.
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ATP结合盒转运蛋白A1 G1051A多态性与突尼斯人群2型糖尿病、脂质和冠状动脉疾病的相关性
背景:atp结合盒转运蛋白A1 (ABCA1)在脂蛋白代谢中起关键作用。这种代谢在2型糖尿病中受到干扰,并与冠状动脉疾病(CAD)有关。因此,我们的目的是研究ABCA1多态性与糖尿病以及这些患者发生冠状动脉疾病的可能性之间的关系。
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