{"title":"Clinical diagnosis and treatment of perineural invasion of head and neck malignant tumors","authors":"Zekun Wang","doi":"10.3760/CMA.J.ISSN.1004-4221.2020.02.015","DOIUrl":null,"url":null,"abstract":"Perineural invasion is a unique biological behavior of tumors via nerve dissemination and metastasis, which is intimately correlated with the recurrence, metastasis and prognosis. With the deepening research, the clinical significance of perineural invasion has been widely recognized. However, due to the low incidence of head and neck neoplasms and the varying incidence of perineural invasion in different anatomical sites and pathological types, high-level evidence-based medical evidence is still lacking. Currently, the pathological mechanism of perineural invasion has not been clearly clarified. No specific treatment has been available for perineural invasion. Therefore, the treatment of perineural invasion of head and neck tumors is an enormous challenge for clinicians. In this article, the current status of clinical diagnosis and treatment of perineural invasion in head and neck malignancies was reviewed. \n \n \nKey words: \nHead and neck neoplasm; Perineural invasion; Diagnosis and treatment","PeriodicalId":10288,"journal":{"name":"中华放射肿瘤学杂志","volume":"29 1","pages":"146-149"},"PeriodicalIF":0.0000,"publicationDate":"2020-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华放射肿瘤学杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1004-4221.2020.02.015","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Perineural invasion is a unique biological behavior of tumors via nerve dissemination and metastasis, which is intimately correlated with the recurrence, metastasis and prognosis. With the deepening research, the clinical significance of perineural invasion has been widely recognized. However, due to the low incidence of head and neck neoplasms and the varying incidence of perineural invasion in different anatomical sites and pathological types, high-level evidence-based medical evidence is still lacking. Currently, the pathological mechanism of perineural invasion has not been clearly clarified. No specific treatment has been available for perineural invasion. Therefore, the treatment of perineural invasion of head and neck tumors is an enormous challenge for clinicians. In this article, the current status of clinical diagnosis and treatment of perineural invasion in head and neck malignancies was reviewed.
Key words:
Head and neck neoplasm; Perineural invasion; Diagnosis and treatment
期刊介绍：
The Chinese Journal of Radiation Oncology is a national academic journal sponsored by the Chinese Medical Association. It was founded in 1992 and the title was written by Chen Minzhang, the former Minister of Health. Its predecessor was the Chinese Journal of Radiation Oncology, which was founded in 1987. The journal is an authoritative journal in the field of radiation oncology in my country. It focuses on clinical tumor radiotherapy, tumor radiation physics, tumor radiation biology, and thermal therapy. Its main readers are middle and senior clinical doctors and scientific researchers. It is now a monthly journal with a large 16-page format and 80 pages of text. For many years, it has adhered to the principle of combining theory with practice and combining improvement with popularization. It now has columns such as monographs, head and neck tumors (monographs), chest tumors (monographs), abdominal tumors (monographs), physics, technology, biology (monographs), reviews, and investigations and research.
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