STRESS IN CHILDREN PATHOLOGY: FROM PSYCHOSOMATICS TO MOLECULAR BIOLOGY

Q4 Medicine Revista Romana de Pediatrie Pub Date : 2021-06-30 DOI:10.37897/rjp.2021.2.1
S. Buzinschi
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Abstract

During childhood, 3 levels of stress were proposed: positive, tolerable and toxic. The toxic stress produced by the strong, frequent and prolonged activation of the body’s response systems is a generator of behavioral and somatic sequelae. Child abuse is present in all social media in different countries. The absence of basic care has devastating effects on social and cognitive development, as found in institutionalized children. Attachment behavior and fear memory are considered stress-related biological systems. The response to stress is driven by the dynamics of cortisol secretion and its interaction with its cellular receptor. It plays a central role in the response to aggression through the process of methylation, decreased gene expression in the hippocampus and increased response to stress. Stress treatment is variable in efficiency and involves preventive measures (family and community), at school, bullying, psychological counseling, trauma-focused psychotherapy, cognitive therapy, through music.
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儿童病理学中的压力:从身心学到分子生物学
在儿童时期,提出了三种压力水平:积极的、可忍受的和有毒的。身体反应系统的强烈、频繁和长期激活所产生的毒性应激是行为和身体后遗症的产生者。虐待儿童现象在不同国家的所有社交媒体上都有。缺乏基本护理对社会和认知发展产生了毁灭性的影响,这在被收容的儿童身上可以发现。依恋行为和恐惧记忆被认为是与压力相关的生物系统。对压力的反应是由皮质醇分泌的动力学及其与细胞受体的相互作用驱动的。它通过甲基化、海马体基因表达减少和对压力的反应增加,在对攻击的反应中发挥着核心作用。压力治疗的效率各不相同,包括预防措施(家庭和社区)、学校、欺凌、心理咨询、创伤心理治疗、认知治疗和音乐。
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来源期刊
CiteScore
0.10
自引率
0.00%
发文量
15
审稿时长
4 weeks
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