Neutrophil-to-Albumin Ratio as A Novel Predictor of Mortality in Patients with Sepsis

Q4 Medicine pzshkhy blyny bn syn Pub Date : 2022-06-01 DOI:10.52547/ajcm.29.1.12
N. Gharebaghi, Mohammad Amin Valizade Hasanloei, Mohammad Fromandi, M. Pashaei
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Abstract

Background and Objective: Sepsis is a syndrome involving physiological, pathological, and biochemical abnormalities caused by infection. Very few studies have been performed to evaluate the prognostic value of the neutrophil-to-albumin ratio. The present study aimed to evaluate the neutrophil-to-albumin ratio in patients with sepsis admitted to the intensive care unit (ICU). Materials and Methods: All patients admitted to the ICU with a diagnosis of sepsis were included in the study. The inclusion criteria entailed the age range of ≥ 18 years, having sepsis, and hospitalization in the ICU for more than two weeks. Results: A total of 75 patients with a mean age of 72.34 years were evaluated, and 57.8% of cases died. There was a significant difference between neutrophils on the second and third days between deceased and discharged patients. The neutrophil-to-albumin ratio at the time of admission, the second day, and the third day were 31.62, 33.36, and 34.31, respectively; nonetheless, no significant difference was observed between the deceased and discharged (P>0.05). Conclusion: As evidenced by the results of this study, the neutrophil-to-albumin ratio in deceased patients was higher than that in discharged ones; however, this difference was not statistically significant. Moreover, neutrophil percentage, duration of mechanical ventilation, and duration of hospitalization in deceased patients were significantly higher, as compared to those in discharged patients.
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中性粒细胞与白蛋白比率作为脓毒症患者死亡率的新预测指标
背景与目的:脓毒症是由感染引起的一种生理、病理、生化异常综合征。很少有研究评估中性粒细胞与白蛋白比值的预后价值。本研究旨在评估入住重症监护室(ICU)的败血症患者中性粒细胞与白蛋白的比率。材料和方法:所有被诊断为败血症的ICU患者都被纳入研究。纳入标准包括年龄≥18岁,患有败血症,在ICU住院两周以上。结果:共评估了75例患者,平均年龄72.34岁,57.8%的患者死亡。死亡患者和出院患者在第二天和第三天的中性粒细胞之间存在显著差异。入院时、第二天和第三天中性粒细胞与白蛋白的比值分别为31.62、33.36和34.31;结论:本研究结果表明,死亡患者中性粒细胞与白蛋白的比值高于出院患者;然而,这种差异在统计学上并不显著。此外,与出院患者相比,死亡患者的中性粒细胞百分比、机械通气持续时间和住院时间显著更高。
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来源期刊
CiteScore
0.30
自引率
0.00%
发文量
16
审稿时长
8 weeks
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