Analysis of recurrent bleeding rate after various surgical interventions in extrahepatic portal hypertension

S. Ismailov, F. Nazyrov, A. V. Devyatov, A. Babadjanov, R. R. Baybekov, A. I. Tuksanov
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Abstract

Aim. To compare the incidence and timing of recurrent bleeding from esophageal and gastric varices against the background of extrahepatic portal hypertension after various interventions.Materials and methods. The research methodology involved analyzing the treatment results of 131 patients with extrahepatic portal hypertension who underwent various surgical interventions from 2006 to 2020. Total dissociation of the gastroesophageal collector was carried out in 57 patients (43.5%), portosystemic shunting – in 51 (38.9%), endoscopic interventions – in 23 (17.6%).Results. When comparing the recurrent bleeding rate, it was found out that the most effective intervention is portosystemic shunting. After endoscopic interventions the bleeding rate is 65.2%, and rebleeding occurs in 13.5 ± 2.9 months. After total dissociation of the gastroesophageal collector, a recurrence-free course was observed in 35.1% of cases (p = 0.014), with timing of 25.9 ± 4.4 months (p < 0.05). In terms of timing, this did not differ from the recurrence after portosystemic shunt surgery (41.4 ± 8.2 months), but was significantly less in the bleeding rate after decompressive surgery (17.6%; p < 0.001). Conclusion. Portosystemic shunt surgery proves to be the most effective intervention in extrahepatic portal hypertension, with a five-year remission in 75% of cases. After dissociative surgeries, 35.1% of patients experienced recurrent bleeding, with average timing of 19.6 months.
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肝外门静脉高压症不同手术干预后复发性出血率分析
的目标。目的比较在肝外门静脉高压背景下食管和胃静脉曲张再出血的发生率和时间。材料和方法。研究方法包括分析2006年至2020年131例肝外门脉高压患者的治疗结果,这些患者接受了各种手术干预。57例(43.5%)患者进行了胃食管收集器的完全分离,51例(38.9%)进行了门系统分流,23例(17.6%)进行了内镜干预。通过对再出血率的比较,发现门静脉系统分流是最有效的干预措施。经内镜干预后出血率为65.2%,再出血时间为13.5±2.9个月。胃食管收集器完全游离后,35.1%的患者无复发(p = 0.014),时间为25.9±4.4个月(p < 0.05)。就时间而言,这与门系统分流手术后的复发(41.4±8.2个月)没有差异,但减压手术后的出血率明显低于(17.6%;P < 0.001)。结论。经证实,门静脉分流术是治疗肝外门静脉高压症最有效的方法,75%的病例可在5年内缓解。游离性手术后,35.1%的患者出现复发性出血,平均时间为19.6个月。
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来源期刊
Annals of HPB Surgery
Annals of HPB Surgery Medicine-Gastroenterology
CiteScore
0.70
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0.00%
发文量
41
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