Distribution of Selected Single Nucleotide Polymorphisms in the Brahmin, Rajput and Bania Populations of Jammu District of Jammu and Kashmir, North India

IF 0.1 4区 生物学 Q4 GENETICS & HEREDITY International Journal of Human Genetics Pub Date : 2021-08-08 DOI:10.31901/24566330.2021/21.02.779
S. Chahal
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Abstract

ABSTRACTA total of 461 randomly selected unrelated subjects belonging to three selected castes populations of Jammu district of Jammu and Kashmir (J&K) viz., the Brahmin, Rajput, and Bania were typed using standard PCRRFLP technique for a battery of five SNPs (Single Nucleotide Polymorphisms) namely NAT2, ADH2, PSCR, T2, and ALAD. The objective of the present study was to characterize these populations genetically and assess the degree of genetic differentiation and genetic affinities among them. The results revealed that the present caste populations were moderately differentiated (GST = 0.0105).The genetic distance analysis demonstrated that the Rajput and Bania were in close genetic affinities while the Brahmin population was somewhat distant. In conclusion, the present investigation documented the underlying genomic uniformity in the people of the Jammu district.
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北印度查谟和克什米尔查谟地区Brahmin、Rajput和Bania人群中选定单核苷酸多态性的分布
摘要使用标准PCRRFLP技术对来自查谟和克什米尔查谟区(J&K)三个选定种姓群体的461名随机选择的无关受试者进行了分型,这三个种姓群体分别是婆罗门、拉吉普特和巴尼亚,共有5个SNP(单核苷酸多态性),即NAT2、ADH2、PSCR、T2和ALAD。本研究的目的是对这些种群进行遗传学表征,并评估它们之间的遗传分化程度和遗传亲缘关系。结果表明,目前的种姓群体具有中等分化(GST=0.0105)。遗传距离分析表明,Rajput和Bania具有密切的遗传亲缘关系,而Brahmin群体则有一定的距离。总之,目前的调查记录了查谟地区人民潜在的基因组一致性。
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