{"title":"Effect of Antimicrobial Peptides and Chemicals Produced by Animals on Aspergillus fumigatus","authors":"Al-Baraa Akram, Glen J. P. McCann","doi":"10.4236/abb.2021.126012","DOIUrl":null,"url":null,"abstract":"The problem of \nmultidrug-resistant pathogens as bacteria, fungi and yeast in addition to the \nrestriction of using antibiotics as growth promoting substances in food has attracted the attention to looking for alternative sources instead of \nconventional antibiotics like natural products which have antimicrobial \nactivity. Much interests and researches have been focused on using natural \nantimicrobial peptides and chemicals extracted from animal secretions and some \ninsect’s venoms as they exhibit antimicrobial activity against pathogens with \nlower resistance and higher synergistic effects if they were given in \ncombination with blends of them. In this paper, some antimicrobial chemicals \nextracted from giraffes are shown in addition to their activity against Aspergillus fumigatus species using \noptical density analysis technique then their Minimum Inhibitory Concentrations \n(MIC) will be determined as well as ICs 50 to measure the potency to inhibit a \nbiological function using programmes like Gene5, graph pad prism as well as \ntesting antimicrobial activity of some chemicals which are provided in animal \nsecretions.","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"生命科学与技术进展(英文)","FirstCategoryId":"1089","ListUrlMain":"https://doi.org/10.4236/abb.2021.126012","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The problem of
multidrug-resistant pathogens as bacteria, fungi and yeast in addition to the
restriction of using antibiotics as growth promoting substances in food has attracted the attention to looking for alternative sources instead of
conventional antibiotics like natural products which have antimicrobial
activity. Much interests and researches have been focused on using natural
antimicrobial peptides and chemicals extracted from animal secretions and some
insect’s venoms as they exhibit antimicrobial activity against pathogens with
lower resistance and higher synergistic effects if they were given in
combination with blends of them. In this paper, some antimicrobial chemicals
extracted from giraffes are shown in addition to their activity against Aspergillus fumigatus species using
optical density analysis technique then their Minimum Inhibitory Concentrations
(MIC) will be determined as well as ICs 50 to measure the potency to inhibit a
biological function using programmes like Gene5, graph pad prism as well as
testing antimicrobial activity of some chemicals which are provided in animal
secretions.