{"title":"Theoretical assessment of the impact of awareness programs on cholera transmission dynamic","authors":"Daudel Tchatat, G. Kolaye, S. Bowong, A. Temgoua","doi":"10.1515/ijnsns-2021-0341","DOIUrl":null,"url":null,"abstract":"Abstract In this paper, we propose and analyse a mathematical model of the transmission dynamics of cholera incorporating awareness programs to study the impact of socio-media and education on cholera outbreaks. These programs induce behavioural changes in the population, which divide the susceptible class into two subclasses, aware individuals and unaware individuals. We first provide a basic study of the model. We compute the Disease-Free Equilibrium (DFE) and derive the basic reproduction number R 0 0 ${\\mathcal{R}}_{0}^{0}$ that determines the extinction and the persistence of the disease. We show that there exists a threshold parameter ξ such that when R 0 0 ≤ ξ < 1 ${\\mathcal{R}}_{0}^{0}\\le \\xi < 1$ , the DFE is globally asymptotically stable, but when ξ ≤ R 0 0 < 1 $\\xi \\le {\\mathcal{R}}_{0}^{0}< 1$ , the model exhibits the phenomenon of backward bifurcation on a feasible region. The model exhibits one endemic equilibrium locally stable when R 0 0 > 1 ${\\mathcal{R}}_{0}^{0} > 1$ and in that condition the DFE is unstable. Various cases for awareness proportions are performed using the critical awareness rate in order to measure the effect of awareness programs on the infected individuals over time. The results we obtained show that the higher implementation of strategies combining awareness programs and therapeutic treatments increase the efficacy of control measures. The numerical simulations of the model are used to illustrate analytical results and give more precision on critical values on the controls actions.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1515/ijnsns-2021-0341","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 2
Abstract
Abstract In this paper, we propose and analyse a mathematical model of the transmission dynamics of cholera incorporating awareness programs to study the impact of socio-media and education on cholera outbreaks. These programs induce behavioural changes in the population, which divide the susceptible class into two subclasses, aware individuals and unaware individuals. We first provide a basic study of the model. We compute the Disease-Free Equilibrium (DFE) and derive the basic reproduction number R 0 0 ${\mathcal{R}}_{0}^{0}$ that determines the extinction and the persistence of the disease. We show that there exists a threshold parameter ξ such that when R 0 0 ≤ ξ < 1 ${\mathcal{R}}_{0}^{0}\le \xi < 1$ , the DFE is globally asymptotically stable, but when ξ ≤ R 0 0 < 1 $\xi \le {\mathcal{R}}_{0}^{0}< 1$ , the model exhibits the phenomenon of backward bifurcation on a feasible region. The model exhibits one endemic equilibrium locally stable when R 0 0 > 1 ${\mathcal{R}}_{0}^{0} > 1$ and in that condition the DFE is unstable. Various cases for awareness proportions are performed using the critical awareness rate in order to measure the effect of awareness programs on the infected individuals over time. The results we obtained show that the higher implementation of strategies combining awareness programs and therapeutic treatments increase the efficacy of control measures. The numerical simulations of the model are used to illustrate analytical results and give more precision on critical values on the controls actions.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.