Abdominal Compartment Syndrome with Super-K (Ketamine) for Super-R(efractory) Status Epilepticus: A Case Report.

IF 1.6 4区 医学 Q3 CLINICAL NEUROLOGY Clinical EEG and Neuroscience Pub Date : 2024-03-01 Epub Date: 2022-10-25 DOI:10.1177/15500594221134920
Prashant A Natteru, Shoba Jayaram, Oriana Sanchez, Kyla Leon, Aditi Mishra, Christa O'Hana Nobleza
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引用次数: 0

Abstract

Refractory status epilepticus is commonly defined as status epilepticus that fails to respond to two or more appropriately dosed intravenous anti-seizure medications including at least one non-benzodiazepine drug. Super-refractory status epilepticus (SRSE) is when status epilepticus continues for ≥24 h despite anesthetic treatment or recurs on an attempted wean of the anesthetic drugs. There is little evidence to guide the management of SRSE. Of late, unconventional therapies have been described in the literature regarding the management of SRSE, with ketamine leading the pack. Studies have noted ketamine's therapeutic efficacy up to 91% in SRSE cessation. Common side effects of ketamine include nausea, vomiting, headache, and hallucinations; but to our knowledge, ketamine has not been implicated in the pathogenesis of abdominal compartment syndrome. We describe a 74-year-old male who developed severe abdominal compartment syndrome in the setting of ketamine infusion for new-onset SRSE to increase awareness about this potential complication.

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腹腔隔室综合征用超k(氯胺酮)治疗超r(难治性)癫痫持续状态:1例报告。
难治性癫痫持续状态通常被定义为对两种或两种以上适当剂量的静脉内抗癫痫药物(包括至少一种非苯二氮卓类药物)没有反应的癫痫持续状态。超难治性癫痫持续状态(SRSE)是指尽管进行了麻醉治疗,但癫痫持续状态仍持续≥24小时,或在尝试戒除麻醉药物后复发。几乎没有证据可以指导SRSE的管理。最近,关于SRSE管理的文献中描述了非常规疗法,其中氯胺酮占主导地位。研究表明,氯胺酮在SRSE停止中的治疗效果高达91%。氯胺酮常见的副作用包括恶心、呕吐、头痛和幻觉;但据我们所知,氯胺酮尚未参与腹腔隔室综合征的发病机制。我们描述了一名74岁的男性,他在新发SRSE患者输注氯胺酮的过程中出现了严重的腹腔室综合征,以提高对这种潜在并发症的认识。
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来源期刊
Clinical EEG and Neuroscience
Clinical EEG and Neuroscience 医学-临床神经学
CiteScore
5.20
自引率
5.00%
发文量
66
审稿时长
>12 weeks
期刊介绍: Clinical EEG and Neuroscience conveys clinically relevant research and development in electroencephalography and neuroscience. Original articles on any aspect of clinical neurophysiology or related work in allied fields are invited for publication.
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