A review on recent developments in the biosynthesis of silver nanoparticles and its biomedical applications

Rizwan Arif, Rahis Uddin
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引用次数: 37

Abstract

Green chemistry is the significant field of research as it offers simple, cost-effective, easy, biocompatible and eco-friendly methods for the synthesis of nanomaterials. With the development of nanotechnology, the synthesis of silver nanoparticles (AgNPs) has become important areas of research due to their various applications in industrial, pharmacological and medicinal fields as they exhibited good antibacterial, antifungal, antioxidant, anti-inflammatory, antiviral, anticoagulant, thrombolytic, cytotoxic and photocatalytic properties due to their chemical stability and good biocompatibility. The size, shape, concentration, agglomeration and some other factors of AgNPs depend on the methods used for the synthesis of nanomaterials. Various methods have been used by the researchers in the last few years for the synthesis of silver nanoparticles (AgNPs) using various microorganisms like bacteria, fungi, algae, different parts of plants, agricultural wastes, arthropods and metabolites of arthropods. The use of microorganisms and plants for the synthesis of silver nanoparticles is very eco-friendly, time-saving and inexpensive methods. In this review, we have discussed the various synthetic methods for the silver nanoparticles (AgNPs) by using microorganisms and plants. Also, the review explores the recent developments in antibacterial, antifungal, antioxidant and cytotoxic properties of silver nanoparticles reported by the researchers during the last decade.

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综述了纳米银的生物合成及其生物医学应用的最新进展
绿色化学是一个重要的研究领域,因为它为纳米材料的合成提供了简单、经济、容易、生物相容性和生态友好的方法。随着纳米技术的发展,纳米银具有良好的化学稳定性和良好的生物相容性,具有良好的抗菌、抗真菌、抗氧化、抗炎、抗病毒、抗凝血、溶栓、细胞毒性和光催化等性能,在工业、药理学和医学等领域得到了广泛的应用,已成为纳米技术研究的重要领域。AgNPs的大小、形状、浓度、团聚和其他一些因素取决于纳米材料的合成方法。在过去的几年里,研究人员使用了各种方法来合成纳米银(AgNPs),这些方法使用了各种微生物,如细菌、真菌、藻类、植物的不同部位、农业废物、节肢动物和节肢动物的代谢物。利用微生物和植物合成纳米银是非常环保、省时和廉价的方法。本文综述了利用微生物和植物合成银纳米粒子的各种方法。综述了近十年来银纳米颗粒在抗菌、抗真菌、抗氧化和细胞毒性等方面的研究进展。Ag +离子还原为Ag 0。研究了纳米颗粒对黑曲霉、白色念珠菌、青霉菌、绿木霉和粘液毛霉的抗真菌活性。研究了大曲霉水提液、乙醇提取物和纳米银对黑曲霉、白色念珠菌、青霉、绿色木霉和Mucor mucedo等真菌的抑菌活性。结果表明,AgNps的抑菌活性在notatum青霉b> Mucor mucdo >青霉>黑曲霉>白色念珠菌中最高(Valsalam, Agastian, Arasu, et al., 2019)。
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