{"title":"Treatment of a case of anxiety disorder with an adverse response to medication","authors":"Sally Jane Nixon , Kersti Seksel","doi":"10.1016/j.jveb.2023.06.002","DOIUrl":null,"url":null,"abstract":"<div><p><span>Following a diagnosis of generalized anxiety disorder, a 19-month-old spayed female French bulldog<span> weighing 11 kg (24 lb) was recommended a treatment plan that included medicating the dog with fluoxetine. Signs indicative of adverse effects to fluoxetine were reported to the </span></span>veterinarian 2 months after a dose increase that had been advised during follow-up at 5 months. Further diagnostic investigation was suggestive of an adverse drug response. Switching the medication to sertraline, with continuing behavior modification and environmental management, resulted in long-term improvement. Long-term follow-up is essential for animals with anxiety disorders, so that the veterinarian can recognize and investigate issues, then adjust the prescribed treatment plan as needed.</p></div>","PeriodicalId":17567,"journal":{"name":"Journal of Veterinary Behavior-clinical Applications and Research","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Veterinary Behavior-clinical Applications and Research","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1558787823000680","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BEHAVIORAL SCIENCES","Score":null,"Total":0}
引用次数: 1
Abstract
Following a diagnosis of generalized anxiety disorder, a 19-month-old spayed female French bulldog weighing 11 kg (24 lb) was recommended a treatment plan that included medicating the dog with fluoxetine. Signs indicative of adverse effects to fluoxetine were reported to the veterinarian 2 months after a dose increase that had been advised during follow-up at 5 months. Further diagnostic investigation was suggestive of an adverse drug response. Switching the medication to sertraline, with continuing behavior modification and environmental management, resulted in long-term improvement. Long-term follow-up is essential for animals with anxiety disorders, so that the veterinarian can recognize and investigate issues, then adjust the prescribed treatment plan as needed.
期刊介绍:
Journal of Veterinary Behavior: Clinical Applications and Research is an international journal that focuses on all aspects of veterinary behavioral medicine, with a particular emphasis on clinical applications and research. Articles cover such topics as basic research involving normal signaling or social behaviors, welfare and/or housing issues, molecular or quantitative genetics, and applied behavioral issues (eg, working dogs) that may have implications for clinical interest or assessment.
JVEB is the official journal of the Australian Veterinary Behaviour Interest Group, the British Veterinary Behaviour Association, Gesellschaft fr Tierverhaltensmedizin und Therapie, the International Working Dog Breeding Association, the Pet Professional Guild, the Association Veterinaire Suisse pour la Medecine Comportementale, and The American Veterinary Society of Animal Behavior.