Antimicrobial and antimycotic photodynamic therapy (review of literature)

Q3 Medicine Biomedical Photonics Pub Date : 2021-04-18 DOI:10.24931/2413-9432-2021-10-1-25-31

D. Y. Semyonov, Y. Vasil'ev, S. Dydykin, E. F. Stranadko, V. Shubin, Y. Bogomazov, V. Morokhotov, A. N. Shcherbyuk, S. Morozov, Y. I. Zakharov

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引用次数: 13

Abstract

This review highlights the possibilities of photodynamic therapy (PDT) using drugs based on chlorin e6, aluminum phthalocyanine, methylene blue as photosensitizers for bacterial and fungal pathologies. This method was developed initially to treat tumor diseases, where it had shown its high efficiency and safety. Now photodynamic therapy is actively used in the treatment of cancers of the skin, bronchi, stomach, cervix, larynx, or other regions. However, numerous studies have been carried out for the entire existence of the method, demonstrating new possibilities of its application. This review highlights a number of studies in which the efficacy and safety of antimicrobial and antimycotic PDT were studied in vivo and in vitro. It has been proven to have a positive effect on the reparative processes in the wound. An experimental study was carried out to study the effectiveness of photodynamic therapy in the treatment of peritonitis in mice. Demonstrated anti-inflammatory potential in the treatment of autoimmune diseases.

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抗菌和抗真菌光动力疗法(文献综述)

这篇综述强调了使用基于氯化氢e6、酞菁铝和亚甲基蓝的药物作为细菌和真菌病理的光敏剂进行光动力治疗（PDT）的可能性。这种方法最初是为了治疗肿瘤疾病而开发的，在那里它显示出了高效和安全性。现在，光动力疗法被积极用于治疗皮肤癌、支气管癌、胃癌、宫颈癌、喉癌或其他区域的癌症。然而，对该方法的整个存在进行了大量研究，证明了其应用的新可能性。这篇综述重点介绍了一些在体内和体外研究抗菌和抗真菌PDT的疗效和安全性的研究。它已被证明对伤口的修复过程有积极影响。进行了一项实验研究，以研究光动力疗法治疗小鼠腹膜炎的有效性。在治疗自身免疫性疾病方面显示出抗炎潜力。

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来源期刊

Biomedical Photonics Medicine-Surgery

CiteScore

1.80

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The main goal of the journal – to promote the development of Russian biomedical photonics and implementation of its advances into medical practice. The primary objectives: - Presentation of up-to-date results of scientific and in research and scientific and practical (clinical and experimental) activity in the field of biomedical photonics. - Development of united Russian media for integration of knowledge and experience of scientists and practitioners in this field. - Distribution of best practices in laser medicine to regions. - Keeping the clinicians informed about new methods and devices for laser medicine - Approval of investigations of Ph.D candidates and applicants.