A narrative review of botanical characteristics, phytochemistry and pharmacology of Valeriana jatamansi jones

Longhua Chinese medicine Pub Date : 2021-03-30 DOI:10.21037/LCM-20-54

Yanhua Ma, Shaofei Pei, Ni He, Qi Lai, M. Zhuang, Z. Bian, Cheng-yuan Lin

{"title":"A narrative review of botanical characteristics, phytochemistry and pharmacology of Valeriana jatamansi jones","authors":"Yanhua Ma, Shaofei Pei, Ni He, Qi Lai, M. Zhuang, Z. Bian, Cheng-yuan Lin","doi":"10.21037/LCM-20-54","DOIUrl":null,"url":null,"abstract":"Valeriana jatamansi Jones (family Caprifoliaceae) is a small perennial herb with multiple pharmacological activities for centuries. This review focuses on the elaborate analysis of Valeriana jatamansi Jones regarding botanical characteristics, phytochemistry and pharmacology. Valepotriates and flavonoids are the major bioactive compounds mainly isolated from the roots/rhizomes. Both the major chemical constituents and different extracts of Valeriana jatamansi Jones are shown to possess the neuroprotective, antidepressant, anti-tumor, gastrointestinal, cytotoxic, anti-virus, antioxidant, sedative and other activities. This review could be helpful to provide a strong bolster for a promising natural resource of drugs for the treatment of various diseases and a long term development in exploring highlighted area. Crude plant of Valeriana jatamansi Jones contains various compounds and a wide range of pharmacological activities. However, further studies are warranted to illuminate the mechanisms responsible for these activities at the molecular levels. Moreover, novel methods and technology should be utilized to explore more components with latent bioactivitities.","PeriodicalId":74086,"journal":{"name":"Longhua Chinese medicine","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Longhua Chinese medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21037/LCM-20-54","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 1

Abstract

Valeriana jatamansi Jones (family Caprifoliaceae) is a small perennial herb with multiple pharmacological activities for centuries. This review focuses on the elaborate analysis of Valeriana jatamansi Jones regarding botanical characteristics, phytochemistry and pharmacology. Valepotriates and flavonoids are the major bioactive compounds mainly isolated from the roots/rhizomes. Both the major chemical constituents and different extracts of Valeriana jatamansi Jones are shown to possess the neuroprotective, antidepressant, anti-tumor, gastrointestinal, cytotoxic, anti-virus, antioxidant, sedative and other activities. This review could be helpful to provide a strong bolster for a promising natural resource of drugs for the treatment of various diseases and a long term development in exploring highlighted area. Crude plant of Valeriana jatamansi Jones contains various compounds and a wide range of pharmacological activities. However, further studies are warranted to illuminate the mechanisms responsible for these activities at the molecular levels. Moreover, novel methods and technology should be utilized to explore more components with latent bioactivitities.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

姜菖蒲的植物特征、植物化学和药理研究综述

日本缬草（Caprifoliaceae）是一种小型多年生草本植物，具有数百年的多种药理活性。本文从植物学特性、植物化学和药理学等方面对日本缬草进行了详细的分析。缬氨酸和黄酮类化合物是主要从根/根茎中分离的生物活性化合物。缬草的主要化学成分和不同提取物均具有神经保护、抗抑郁、抗肿瘤、胃肠道、细胞毒性、抗病毒、抗氧化、镇静等活性。这篇综述可能有助于为治疗各种疾病的药物的有前景的自然资源和探索重点领域的长期发展提供强有力的支持。缬草粗品含有多种化合物，具有广泛的药理活性。然而，需要进一步的研究来阐明分子水平上这些活动的机制。此外，应该利用新的方法和技术来探索更多具有潜在生物活性的成分。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Longhua Chinese medicine

自引率

0.00%

发文量